Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4574160 | 0.90 | MAOA (0.42) | MAOAMAOBCA2CA12CA14 | |
| SCHEMBL6535041 | 0.87 | MAOA (0.44) | MAOAMAOBCA2CA12CA14 | |
| SCHEMBL9612246 | 0.85 | MAOA (0.43) | MAOAMAOBCA2CA12CA14 | |
| SCHEMBL871751 | 0.83 | CA2 (0.37) | CA2CA12CA14TDP1PTPRC | |
| SCHEMBL3297916 | 0.79 | MAOA (0.40) | MAOAMAOBCA2CA12CA14 | |
| SCHEMBL18407102 | 0.79 | MAOA (0.40) | MAOAMAOBCA2CA12CA14 | |
| SCHEMBL308856 | 0.79 | EPHX2 (0.36) | CA2CA12CA14TDP1CYP2D6 | |
| SCHEMBL783009 | 0.78 | CA2 (0.41) | MAOAMAOBCA2CA12CA14 | |
| SCHEMBL12450077 | 0.78 | MAOA (0.39) | MAOAMAOBCA2CA12CA14 | |
| SCHEMBL22235058 | 0.78 | MAOA (0.39) | MAOAMAOBCA2CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2128134-A1 | SULFONYLUREA DERIVATIVE CAPABLE OF SELECTIVELY INHIBITING MMP-13 | Shionogi&Co., Ltd. (JP) | 2009-12-02 | — | — | EP | disclosed |