SCHEMBL440079

SCHEMBL440079

CCC(O)P(=O)(O)CCP(=O)(O)C(O)CC

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FDPS P14324 3/20 0.40
LAP3 P28838 1/20 0.40
METAP1 P53582 2/20 0.34
MMP1 P03956 2/20 0.34
MMP2 P08253 2/20 0.34
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
MMP8 P22894 1/20 0.34
CA9 Q16790 1/20 0.34
LPAR3 Q9UBY5 3/20 0.33
LPAR2 Q9HBW0 1/20 0.33
MEN1 O00255 1/20 0.33
CYP1A2 P05177 1/20 0.33
KMT2A Q03164 1/20 0.33
TSHR P16473 1/20 0.33
MMP3 P08254 1/20 0.33
TRPM8 Q7Z2W7 1/20 0.31
ANPEP P15144 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10585820 0.90 FDPS (0.42) FDPSLAP3METAP1LPAR3LPAR2
SCHEMBL1694470 0.77
SCHEMBL14278053 0.77
SCHEMBL3796270 0.73 LAP3 (0.39) FDPSLAP3MMP1MMP2CA12
Phosphoric Acid SCHEMBL8842709 0.69 LAP3 (0.48) FDPSLAP3METAP1MMP1MMP2
Phosphoric Acid SCHEMBL8842719 0.69 LAP3 (0.48) FDPSLAP3METAP1MMP1MMP2
Phosphoric Acid SCHEMBL1360058 0.69 LAP3 (0.48) FDPSLAP3METAP1MMP1MMP2
SCHEMBL1085804 0.69 LAP3 (0.36) FDPSLAP3MMP1MMP2CA12
Phosphoric Acid SCHEMBL2676634 0.69 FDPS (0.55) FDPSLAP3METAP1LPAR3LPAR2
Phosphonic Acid SCHEMBL8592839 0.69 LAP3 (0.42) FDPSLAP3METAP1MMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120064790-A1 Ethylene Diphosphinic Acids CLARIANT FINANCE (BVI) LIMITED (VG) 2012-03-15 US disclosed
US-8084518-B2 Ethylenebis(hydroxyalkylphosphinic acid) and salts thereof CLARIANT FINANCE (BVI) LIMITED (VG) 2011-12-27 US disclosed
EP-2081942-B1 ETHYLENE DIPHOSPHINIC ACIDS CLARIANT FINANCE BVI LTD (VG) 2011-12-14 EP disclosed
US-20100093239-A1 Ethylene Diphosphinic Acids CLARIANT INTERNATIONAL LTD. (CH) 2010-04-15 US disclosed