Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 18/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12663027 | 0.93 | NR3C1 (0.56) | NR3C1PGRCYP3A4CYP2C9TRPV1 | |
| SCHEMBL12663246 | 0.92 | NR3C1 (0.54) | NR3C1 | |
| SCHEMBL476766 | 0.89 | NR3C1 (0.66) | NR3C1PGRCYP3A4CYP2C9 | |
| SCHEMBL12663030 | 0.86 | NR3C1 (0.54) | NR3C1PGRCYP3A4CYP2C9 | |
| SCHEMBL12663247 | 0.84 | NR3C1 (0.56) | NR3C1 | |
| SCHEMBL476735 | 0.82 | NR3C1 (0.68) | NR3C1PGRCYP3A4CYP2C9 | |
| SCHEMBL4400812 | 0.82 | NR3C1 (0.47) | NR3C1PGRCYP3A4CYP2C9TRPV1 | |
| SCHEMBL476762 | 0.81 | NR3C1 (0.67) | NR3C1 | |
| SCHEMBL4396956 | 0.79 | NR3C1 (0.56) | NR3C1 | |
| SCHEMBL12663031 | 0.79 | NR3C1 (0.56) | NR3C1PGRCYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7947727-B2 | Compounds | GlaxoGroupLimited (GB) | 2011-05-24 | — | — | US | disclosed |
| US-20100120883-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2010-05-13 | — | — | US | disclosed |
| EP-2081910-A1 | NOVEL COMPOUNDS | Glaxo Group Limited (GB) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008043789-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2008-04-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120883-A1 | NOVEL COMPOUNDS | TSLP, LTB4R2, LTB4R | NR3C1 267/4885PGR 1065/4885CYP3A4 257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.