Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.55 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.54 |
| ▸ | HTR3B | O95264 | 2/20 | 0.54 |
| ▸ | HTR3A | P46098 | 2/20 | 0.54 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.54 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.54 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.54 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.54 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.54 |
| ▸ | PLAU | P00749 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | STAT3 | P40763 | 1/20 | 0.52 |
| ▸ | STAT1 | P42224 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17830834 | 0.90 | CES2 (0.52) | ESR2HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL22594341 | 0.89 | CYP2D6 (0.63) | ESR2HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL16382908 | 0.89 | CYP2D6 (0.53) | ESR2HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL11421052 | 0.89 | CYP2D6 (0.53) | ESR2HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL11421050 | 0.89 | CYP2D6 (0.53) | ESR2HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL9349552 | 0.81 | ESR2 (0.60) | ESR2SMN1; SMN2NPC1MAPTRAB9A | |
| SCHEMBL25640319 | 0.80 | HTR3E (0.44) | ESR2HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL25640339 | 0.80 | HTR3E (0.44) | ESR2HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL15073401 | 0.78 | NOS3 (0.52) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL27552961 | 0.77 | HTR3E (0.61) | ESR2HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173276-B2 | Materials for electroluminescence and the utilization thereof | MERCK PATENT GMBH (DE) | 2012-05-08 | — | — | US | disclosed |
| US-20100102305-A1 | MATERIALS FOR ELECTROLUMINESCENCE AND THE UTILIZATION THEREOF | MERCK PATENT GMBH (DE) | 2010-04-29 | — | — | US | disclosed |
| US-7659540-B2 | Materials for electroluminescence and the utilization thereof | MERCK PATENT GMBH (DE) | 2010-02-09 | — | — | US | disclosed |
| US-20070080343-A1 | New materials for electroluminescence and the utilization thereof | MERCK PATENT GMBH (DE) | 2007-04-12 | — | — | US | disclosed |