Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | ACR | P10323 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12692038 | 0.88 | POLB (0.40) | KMT2AALDH1A1POLBLMNA | |
| SCHEMBL2899524 | 0.81 | CHRM2 (0.47) | — | |
| SCHEMBL2839505 | 0.79 | SCN1A (0.47) | KMT2AMAPTMEN1SMN1; SMN2EGFR | |
| SCHEMBL2898584 | 0.74 | BCHE (0.45) | KMT2AMAPTMEN1ALDH1A1TDP1 | |
| SCHEMBL27052388 | 0.73 | MAPT (0.41) | KMT2AMAPTMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL15607733 | 0.72 | MAPT (0.56) | KMT2AMAPTMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL6475721 | 0.72 | SRD5A2 (0.40) | MAPTALDH1A1SRD5A2HPGD | |
| SCHEMBL3395142 | 0.71 | KDM4E (0.36) | ALDH1A1TDP1LMNA | |
| SCHEMBL10908306 | 0.71 | TRPV1 (0.62) | MAPTALDH1A1MAPK1HPGD | |
| SCHEMBL14002248 | 0.70 | MEN1 (0.43) | KMT2AMEN1ALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094760-B1 | COMPOSITIONS CURABLE BY RING OPENING METATHESIS POLYMERIZATION AT LOW TEMPERATURES AND THEIR APPLICATION IN THE DENTAL FIELD | 3M INNOVATIVE PROPERTIES CO (US) | 2017-05-31 | — | — | EP | disclosed |
| US-8431625-B2 | Compositions curable by ring opening metathesis polymerization at low temperatures and their application in the dental field | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-04-30 | — | — | US | disclosed |
| US-8431625-B2 | Compositions curable by ring opening metathesis polymerization at low temperatures and their application in the dental field | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-04-30 | — | — | US | disclosed |
| US-8178604-B2 | Solid materials obtainable by ring-opening metathesis polymerization | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-05-15 | — | — | US | disclosed |
| US-8178604-B2 | Solid materials obtainable by ring-opening metathesis polymerization | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-05-15 | — | — | US | disclosed |
| EP-1815838-B1 | Solid materials obtainable by the ring-opening methathesis polymerization | 3M INNOVATIVE PROPERTIES CO (US) | 2010-09-08 | — | — | EP | disclosed |
| US-20100036015-A1 | COMPOSITIONS CURABLE BY RING OPENING METATHESIS POLYMERIZATION AT LOW TEMPERATURES AND THEIR APPLICATION IN THE DENTAL FIELD | 3M INNOVATIVE PROPERTIES COMPANY | 2010-02-11 | — | — | US | disclosed |
| US-20100036015-A1 | COMPOSITIONS CURABLE BY RING OPENING METATHESIS POLYMERIZATION AT LOW TEMPERATURES AND THEIR APPLICATION IN THE DENTAL FIELD | 3M INNOVATIVE PROPERTIES COMPANY | 2010-02-11 | — | — | US | disclosed |
| US-20090088494-A1 | SOLID MATERIALS OBTAINABLE BY RING-OPENING METATHESIS POLYMERIZATION | 3M INNOVATIVE PROPERTIES COMPANY | 2009-04-02 | — | — | US | disclosed |
| US-20090088494-A1 | SOLID MATERIALS OBTAINABLE BY RING-OPENING METATHESIS POLYMERIZATION | 3M INNOVATIVE PROPERTIES COMPANY | 2009-04-02 | — | — | US | disclosed |
| EP-1942125-A1 | Compositions curable by ring opening metathesis polymerarization at low temperatures and their application in the dental field | 3M Innovative Properties Company (US) | 2008-07-09 | — | — | EP | disclosed |
| WO-2008077001-A1 | COMPOSITIONS CURABLE BY RING OPENING METATHESIS POLYMERIZATION AT LOW TEMPERATURES AND THEIR APPLICATION IN THE DENTAL FIELD | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2008-06-26 | — | — | WO | disclosed |
| WO-2007089801-A1 | SOLID MATERIALS OBTAINABLE BY RING-OPENING METATHESIS POLYMERIZATION | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-08-09 | — | — | WO | disclosed |
| EP-1815838-A1 | Solid materials obtainable by the ring-opening methathesis polymerization | 3M Innovative Properties Company (US) | 2007-08-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100036015-A1 | COMPOSITIONS CURABLE BY RING OPENING METATHESIS POLYMERIZATION AT LOW TEMPERATURES AND THEIR APPLICATION IN THE DENTAL FIELD | DNMT3B, HMBS, MMAB | KMT2A 1341/4885MAPT 545/4885MEN1 784/4885 |
| US-20090088494-A1 | SOLID MATERIALS OBTAINABLE BY RING-OPENING METATHESIS POLYMERIZATION | MMAB, DNMT3B, RHEB | KMT2A 1609/4885MAPT 1245/4885MEN1 247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.