Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4401298 | 1.00 | KMT2A (0.41) | KMT2AALDH1A1TSHRKDM4EHPGD | |
| SCHEMBL4405985 | 1.00 | KMT2A (0.41) | KMT2AALDH1A1TSHRKDM4EHPGD | |
| SCHEMBL4409388 | 0.98 | CNR1 (0.40) | KMT2AALDH1A1TSHRKDM4EHPGD | |
| SCHEMBL4409384 | 0.98 | CNR1 (0.40) | KMT2AALDH1A1TSHRKDM4EHPGD | |
| SCHEMBL4400068 | 0.95 | ALDH1A1 (0.41) | KMT2AALDH1A1TSHRKDM4EHPGD | |
| SCHEMBL4400078 | 0.95 | ALDH1A1 (0.41) | KMT2AALDH1A1TSHRKDM4EHPGD | |
| SCHEMBL4397302 | 0.91 | TSHR (0.44) | KMT2AALDH1A1TSHRKDM4EMAPK1 | |
| SCHEMBL4397300 | 0.91 | TSHR (0.44) | KMT2AALDH1A1TSHRKDM4EMAPK1 | |
| SCHEMBL4401025 | 0.91 | TSHR (0.44) | KMT2AALDH1A1TSHRKDM4EMAPK1 | |
| SCHEMBL4404009 | 0.89 | GNRHR (0.42) | ALDH1A1TSHRKDM4EMAPK1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7632946-B2 | Naphthyridine-based antibacterial compositions | ABBOTT LABORATORIES (US) | 2009-12-15 | — | — | US | disclosed |
| US-20070088040-A1 | Antibacterial compounds | ABBVIE INC. | 2007-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070088040-A1 | Antibacterial compounds | MRPL21, FDPS, PGLS | KMT2A 4523/4885ALDH1A1 2936/4885TSHR 4543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.