SCHEMBL440146

SCHEMBL440146

CCc1cc(N)ccc1O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCI P41743 1/20 0.68
ACHE P22303 3/20 0.66
BACE1 P56817 1/20 0.60
ESR2 Q92731 4/20 0.53
ESR1 P03372 3/20 0.53
PDE10A Q9Y233 1/20 0.52
HSP90AA1 P07900 1/20 0.47
HSP90AB1 P08238 1/20 0.47
HSD17B1 P14061 1/20 0.47
CASP1 P29466 2/20 0.47
ALOX15 P16050 2/20 0.47
HSD17B10 Q99714 2/20 0.47
KDM4E B2RXH2 2/20 0.47
ALDH1A1 P00352 2/20 0.47
CYP3A4 P08684 2/20 0.47
MEN1 O00255 1/20 0.47
TNF P01375 1/20 0.47
HSPD1 P10809 1/20 0.47
THRB P10828 1/20 0.47
CYP2C9 P11712 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4856507 0.98 ACHE (0.69) PRKCIACHEBACE1ESR2ESR1
SCHEMBL5381058 0.83 PRKCI (0.63) PRKCIACHEBACE1ESR2ESR1
SCHEMBL9204022 0.82 PRKCI (0.57) PRKCIACHEBACE1ESR2PDE10A
SCHEMBL454663 0.82 CASP1 (0.52) PRKCIACHEBACE1ESR2ESR1
SCHEMBL11682542 0.82 PRKCI (0.49) PRKCIACHEBACE1ESR2ESR1
SCHEMBL30597925 0.81 PRKCI (0.61) PRKCIACHEBACE1ESR2PDE10A
SCHEMBL29358019 0.81 PRKCI (0.61) PRKCIACHEBACE1ESR2PDE10A
SCHEMBL111004 0.81 PRKCI (0.61) PRKCIACHEBACE1ESR2PDE10A
SCHEMBL111109 0.81 PRKCI (1.00) PRKCIACHEBACE1PDE10AHSP90AA1
SCHEMBL29565648 0.81 PRKCI (1.00) PRKCIACHEBACE1PDE10AHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117164745-A Composite material for microporous membrane, composite ion exchange membrane and application of composite material 国家电投集团氢能科技发展有限公司 2023-12-05 CN claimed
CN-117126311-A Polymer, composite, ion exchange membrane and preparation method and application thereof 国家电投集团氢能科技发展有限公司 2023-11-28 CN claimed
CN-116808842-B Modified microporous membrane, composite ion exchange membrane, and preparation methods and applications thereof 国家电投集团氢能科技发展有限公司 2023-10-27 CN claimed
CN-116808842-A Modified microporous membrane, composite ion exchange membrane, and preparation methods and applications thereof 国家电投集团氢能科技发展有限公司 2023-09-29 CN claimed
CN-109053800-A Quaternary alkylphosphonium salt support chiral amino-thiocarbamide and its preparation method and application 湖北大学 2018-12-21 CN claimed
EP-2004164-B1 PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING INFLAMMATORY DISEASES NEUROTECH PHARMACEUTICALS CO LTD (KR) 2018-08-08 EP claimed
US-9102589-B2 Reactive distillation process for preparation of acetaminophen GRANULES INDIA LIMITED (IN) 2015-08-11 US claimed
CN-103483214-A Compound, preparation method thereof and applications of compound in prevention of ulcerative colitis UNIV XI AN JIAOTONG 2014-01-01 CN claimed
US-20120065423-A1 REACTIVE DISTILLATION PROCESS FOR PREPARATION OF ACETAMINOPHEN GRANULES INDIA LIMITED (IN) 2012-03-15 US claimed
CN-1264498-C Primary intermediates for oxidative dyeing of hair PROCTER & GAMBLE (US) 2006-07-19 CN claimed
WO-2001097754-A2 AGENT FOR DYEING FIBRES CONTAINING KERATIN, CONTAINING AT LEAST ONE QUINOXALINE DERIVATIVE HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-12-27 WO claimed
WO-2001089587-A2 AGENTS FOR DYEING FIBRES CONTAINING KERATIN HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-11-29 WO claimed
WO-2001089460-A2 COLORANT FOR FIBRES CONTAINING KERATIN HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-11-29 WO claimed
EP-1139988-A1 AGENT FOR DYING KERATIN FIBERS Henkel Kommanditgesellschaft auf Aktien (DE) 2001-10-10 EP claimed
WO-2001047485-A1 AGENT FOR COLOURING FIBRES CONTAINING KERATIN HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-07-05 WO claimed
WO-2001030312-A1 MEANS FOR COLOURING KERATIN CONTAINING FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-05-03 WO claimed
WO-2001010398-A1 AGENT FOR DYING KERATIN FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2001-02-15 WO claimed
WO-2000038633-A1 AGENT FOR DYING KERATIN FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2000-07-06 WO claimed
WO-2000038634-A1 AGENT FOR DYING KERATIN FIBERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2000-07-06 WO claimed
EP-0269914-A1 Composition and process for the oxidative dyeing of hair on the basis of 3-(2',2',2'-trifluorethyl)aminophenol derivatives, and 3-(2',2',2'-trifluorethyl)aminophenol derivatives Wella Aktiengesellschaft (DE) 1988-06-08 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120065423-A1 REACTIVE DISTILLATION PROCESS FOR PREPARATION OF ACETAMINOPHEN CYP2E1, NAT1, ADH1A PRKCI 4323/4885ACHE 625/4885BACE1 4217/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.