SCHEMBL4402188

SCHEMBL4402188

CCc1ccccc1N(c1ccc(C)cc1)c1ccc(C=Cc2ccccc2C=Cc2ccc(N(c3ccc(C)cc3)c3ccccc3CC)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FGF23 Q9GZV9 1/20 0.47
NFE2L2 Q16236 4/20 0.46
APP P05067 2/20 0.40
CTDSP1 Q9GZU7 1/20 0.39
TRPM8 Q7Z2W7 2/20 0.38
CHAT P28329 1/20 0.38
RELA Q04206 1/20 0.37
ALDH1A1 P00352 5/20 0.36
MAPT P10636 4/20 0.36
HPGD P15428 3/20 0.36
KDM4E B2RXH2 3/20 0.36
LMNA P02545 3/20 0.36
SNCA P37840 1/20 0.35
HTT P42858 2/20 0.35
NPSR1 Q6W5P4 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
CYP3A4 P08684 1/20 0.35
MEN1 O00255 2/20 0.35
RAB9A P51151 2/20 0.35
KMT2A Q03164 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12763698 0.95 FGF23 (0.43) FGF23NFE2L2APPCTDSP1TRPM8
SCHEMBL4400830 0.94 CTDSP1 (0.42) FGF23NFE2L2CTDSP1TRPM8RELA
SCHEMBL5937678 0.92 FGF23 (0.41) FGF23NFE2L2APPCTDSP1TRPM8
SCHEMBL12680420 0.91 CTDSP1 (0.47) NFE2L2CTDSP1TRPM8CHATRELA
SCHEMBL12763685 0.89 CTDSP1 (0.39) FGF23NFE2L2CTDSP1TRPM8RELA
SCHEMBL4405007 0.87 NFE2L2 (0.45) NFE2L2APPCTDSP1TRPM8RELA
SCHEMBL14526445 0.85 NFE2L2 (0.54) FGF23NFE2L2APPCTDSP1TRPM8
SCHEMBL12640411 0.85 RELA (0.47) APPCTDSP1TRPM8CHATRELA
SCHEMBL4400836 0.85 RELA (0.46) APPCTDSP1CHATRELAALDH1A1
SCHEMBL21886397 0.84 CYP2C19 (0.41) ALDH1A1HPGDKDM4ELMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8507163-B2 Method of manufacturing image bearing member, image bearing member, and image forming apparatus RICOH COMPANY, LTD. (JP) 2013-08-13 US disclosed
US-8507163-B2 Method of manufacturing image bearing member, image bearing member, and image forming apparatus RICOH COMPANY, LTD. (JP) 2013-08-13 US disclosed
US-8486595-B2 Image bearing member, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2013-07-16 US disclosed
US-20130022902-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING METHOD AND APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2013-01-24 US disclosed
US-8273513-B2 Image forming apparatus, process cartridge, and image bearing member RICOH COMPANY, LIMITED (JP) 2012-09-25 US disclosed
US-8178266-B2 Electrophotographic photoreceptor, image forming apparatus using the electrophotographic photoreceptor, and method of producing electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2012-05-15 US disclosed
US-8178266-B2 Electrophotographic photoreceptor, image forming apparatus using the electrophotographic photoreceptor, and method of producing electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2012-05-15 US disclosed
US-8173343-B2 Electrophotographic photoconductor, image forming apparatus using the same, and process cartridge RICOH COMPANY, LTD. (JP) 2012-05-08 US disclosed
US-20110159419-A1 IMAGE BEARING MEMBER, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD (JP) 2011-06-30 US disclosed
US-20110159419-A1 IMAGE BEARING MEMBER, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD (JP) 2011-06-30 US disclosed
US-7879519-B2 electrostatic latent imaging; photoconductors; charge generating layer comprises titanyl phthalocyanine pigment RICOH COMPANY LIMITED (JP) 2011-02-01 US disclosed
US-7879519-B2 electrostatic latent imaging; photoconductors; charge generating layer comprises titanyl phthalocyanine pigment RICOH COMPANY LIMITED (JP) 2011-02-01 US disclosed
US-20100330475-A1 IMAGE FORMING APPARATUS, PROCESS CARTRIDGE, AND IMAGE BEARING MEMBER RICOH COMPANY LIMITED (JP) 2010-12-30 US disclosed
US-20100015538-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING APPARATUS USING THE SAME, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2010-01-21 US disclosed
US-20090324281-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING APPARATUS USING THE ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2009-12-31 US disclosed
US-20090324281-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING APPARATUS USING THE ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2009-12-31 US disclosed
US-20090185821-A1 Electrophotographic photoreceptor, and image formihg appratus and process cartridge using same RICOH COMPANY, LTD (JP) 2009-07-23 US disclosed
US-20090180788-A1 Image forming apparatus, and image forming method RICOH COMPANY, LTD. (JP) 2009-07-16 US disclosed
US-20080292981-A1 IMAGE BEARING MEMBER AND IMAGE FORMING APPARATUS USING THE SAME RICOH COMPANY LIMITED (JP) 2008-11-27 US disclosed
US-20080292981-A1 IMAGE BEARING MEMBER AND IMAGE FORMING APPARATUS USING THE SAME RICOH COMPANY LIMITED (JP) 2008-11-27 US disclosed