Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | NR1D1 | P20393 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13427909 | 0.97 | MAOA (0.36) | MAOAMAOBNR1D1KDM4ETDP1 | |
| SCHEMBL6536011 | 0.97 | MAOA (0.36) | MAOAMAOBNR1D1KDM4ETDP1 | |
| SCHEMBL8019850 | 0.94 | MAOA (0.35) | MAOAMAOBNR1D1CA14CA12 | |
| SCHEMBL19016239 | 0.94 | MAOA (0.35) | MAOAMAOBNR1D1CA14CA12 | |
| SCHEMBL23130697 | 0.92 | TDP1 (0.34) | MAOAMAOBNR1D1KDM4ELMNA | |
| SCHEMBL14524031 | 0.91 | MAOA (0.35) | MAOAMAOB | |
| SCHEMBL25477299 | 0.91 | MAOA (0.32) | MAOAMAOB | |
| SCHEMBL22234380 | 0.91 | MAOA (0.33) | MAOAMAOBKDM4ECA14CA12 | |
| SCHEMBL21392316 | 0.90 | CA12 (0.36) | MAOAMAOBCYP2C19CA14CA12 | |
| SCHEMBL18636575 | 0.89 | MAOA (0.35) | MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720575-B1 | THERAPEUTIC AND DIAGNOSTIC CONJUGATES FOR USE WITH MULTISPECIFIC ANTIBODIES | IMMUNOMEDICS INC (US) | 2015-05-20 | — | — | EP | disclosed |
| EP-1720575-B1 | THERAPEUTIC AND DIAGNOSTIC CONJUGATES FOR USE WITH MULTISPECIFIC ANTIBODIES | IMMUNOMEDICS INC (US) | 2015-05-20 | — | — | EP | disclosed |
| US-8158573-B2 | Therapeutic and diagnostic conjugates for use with multispecific antibodies | IMMUNOMEDICS, INC. (US) | 2012-04-17 | — | — | US | disclosed |
| US-8158573-B2 | Therapeutic and diagnostic conjugates for use with multispecific antibodies | IMMUNOMEDICS, INC. (US) | 2012-04-17 | — | — | US | disclosed |
| US-20120063993-A1 | THERAPEUTIC AND DIAGNOSTIC CONJUGATES FOR USE WITH MULTISPECIFIC ANTIBODIES | IMMUNOMEDICS, INC. (US) | 2012-03-15 | — | — | US | disclosed |
| US-20120063993-A1 | THERAPEUTIC AND DIAGNOSTIC CONJUGATES FOR USE WITH MULTISPECIFIC ANTIBODIES | IMMUNOMEDICS, INC. (US) | 2012-03-15 | — | — | US | disclosed |
| US-7405320-B2 | Therapeutic and diagnostic conjugates for use with multispecific antibodies | IMMUNOMEDICS, INC. (US) | 2008-07-29 | — | — | US | disclosed |
| US-7405320-B2 | Therapeutic and diagnostic conjugates for use with multispecific antibodies | IMMUNOMEDICS, INC. (US) | 2008-07-29 | — | — | US | disclosed |
| US-20050002945-A1 | Therapeutic and diagnostic conjugates for use with multispecific antibodies | IMMUNOMEDICS, INC. | 2005-01-06 | — | — | US | disclosed |
| WO-2001002339-A1 | VERSATILE METHOD FOR THE SYNTHESIS OF ISO-DTPA | MALLINCKRODT INC. (US) | 2001-01-11 | — | — | WO | disclosed |
| WO-2000058267-A1 | ENHANCED SELECTIVITY IN THE SYNTHESIS OF DTPA ESTERS FOM DIETHYLENETRIAMINE | MALLINCKRODT INC. (US) | 2000-10-05 | — | — | WO | disclosed |
| WO-2000058265-A1 | PREPARATION OF DTPA ESTERS WITH DIFFERENT ESTER GROUPS | MALLINCKRODT INC. (US) | 2000-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050002945-A1 | Therapeutic and diagnostic conjugates for use with multispecific antibodies | TST, GLUL, TGM3 | MAOA 3866/4885MAOB 3829/4885NR1D1 3735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.