SCHEMBL5828609

SCHEMBL5828609

C[C@H](N)C(=O)On1cccn1

nearest known ligand 0.41

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL440250 0.75
SCHEMBL278457 0.75
SCHEMBL10751495 0.74 NOS1 (0.32) NOS1
SCHEMBL128494 0.72
SCHEMBL30829069 0.71 LMNA (0.33)
SCHEMBL2853189 0.71
SCHEMBL1577982 0.71 GRIN2D (0.31)
SCHEMBL601253 0.70 FDPS (0.33) NOS1
SCHEMBL28346497 0.70 KDM4E (0.31)
SCHEMBL11242896 0.70 KMT2A (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3912641-B1 HYDROPHILIC DRUG-LINKER COMPOUNDS SEAGEN INC (US) 2024-11-06 EP claimed
US-20230132738-A1 HYDROPHILIC ANTIBODY-DRUG CONJUGATES SEAGEN INC (US) 2023-05-04 US claimed
US-11510959-B2 Hydrophilic antibody-drug conjugates SEAGEN INC. (US) 2022-11-29 US claimed
EP-3912641-A1 HYDROPHILIC DRUG-LINKER COMPOUNDS Seagen Inc. (US) 2021-11-24 EP claimed
US-20210283210-A1 HYDROPHILIC ANTIBODY-DRUG CONJUGATES SEAGEN INC (US) 2021-09-16 US claimed
EP-3107557-B1 HYDROPHILIC ANTIBODY-DRUG CONJUGATES SEAGEN INC (US) 2021-06-09 EP claimed
US-10933112-B2 Hydrophilic antibody-drug conjugates SEAGEN INC. (US) 2021-03-02 US claimed
US-20170216391-A1 HYDROPHILIC ANTIBODY-DRUG CONJUGATES SEATTLE GENETICS, INC. (US) 2017-08-03 US claimed
EP-3107557-A1 HYDROPHILIC ANTIBODY-DRUG CONJUGATES Seattle Genetics, Inc. (US) 2016-12-28 EP claimed
CN-106029083-A Hydrophilic antibody-drug conjugates 西雅图基因公司 2016-10-12 CN claimed
WO-2015123679-A1 HYDROPHILIC ANTIBODY-DRUG CONJUGATES SEATTLE GENETICS, INC. (US) 2015-08-20 WO claimed
US-12257281-B2 Hydrophilic antibody-drug conjugates SEAGEN INC. (US) 2025-03-25 US disclosed
EP-3912641-B1 HYDROPHILIC DRUG-LINKER COMPOUNDS SEAGEN INC (US) 2024-11-06 EP disclosed
US-20240115648-A1 HYDROPHILIC ANTIBODY-DRUG CONJUGATES SEAGEN INC (US) 2024-04-11 US disclosed
US-20230132738-A1 HYDROPHILIC ANTIBODY-DRUG CONJUGATES SEAGEN INC (US) 2023-05-04 US disclosed
EP-1191106-B1 Process for the fermentative preparation of non-proteinogenic L-amino acids CONSORTIUM ELEKTROCHEM IND (DE) 2004-04-28 EP disclosed
US-6579705-B2 Generating preferential amino acid sequences; obtain adjusted amino acid, incubate with enzyme, recover amino acid CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 2003-06-17 US disclosed
EP-1247869-A1 Process for the production of non-proteinogenic amino acids Consortium für elektrochemische Industrie GmbH (DE) 2002-10-09 EP disclosed
US-20020039767-A1 Process for producing non-proteinogenic L-amino acids by fermentation CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH 2002-04-04 US disclosed
EP-1191106-A1 Verfahren zur fermentativen Herstellung von nicht-proteinogenen L-Aminosäuren Consortium für elektrochemische Industrie GmbH (DE) 2002-03-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020039767-A1 Process for producing non-proteinogenic L-amino acids by fermentation CBS, BCAT2, BCAT1 NOS1 142/4885
US-20210283210-A1 HYDROPHILIC ANTIBODY-DRUG CONJUGATES CD44, FCGR1A, FCGR2A NOS1 4418/4885
US-11510959-B2 Hydrophilic antibody-drug conjugates CD44, FCGR1A, FCGR2A NOS1 4418/4885
US-12257281-B2 Hydrophilic antibody-drug conjugates CD44, FCGR1A, FCGR2A NOS1 4418/4885
US-20240115648-A1 HYDROPHILIC ANTIBODY-DRUG CONJUGATES CD44, FCGR1A, FCGR2A NOS1 4418/4885
US-20170216391-A1 HYDROPHILIC ANTIBODY-DRUG CONJUGATES CD44, FCGR1A, FCGR2A NOS1 4418/4885
US-10933112-B2 Hydrophilic antibody-drug conjugates CD44, FCGR1A, FCGR2A NOS1 4418/4885
US-20230132738-A1 HYDROPHILIC ANTIBODY-DRUG CONJUGATES CD44, FCGR1A, FCGR2A NOS1 4418/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.