Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SHBG | P04278 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4402682 | 1.00 | TSHR (0.44) | TSHRNPC1MAPTRAB9ASHBG | |
| SCHEMBL4402677 | 1.00 | TSHR (0.44) | TSHRNPC1MAPTRAB9ASHBG | |
| SCHEMBL17275040 | 0.91 | SHBG (0.41) | SHBGESR1ESR2 | |
| SCHEMBL4406527 | 0.82 | CYP2C9 (0.44) | SHBG | |
| SCHEMBL4406531 | 0.82 | CYP2C9 (0.44) | SHBG | |
| SCHEMBL4399596 | 0.82 | CYP2C9 (0.44) | SHBG | |
| SCHEMBL4399833 | 0.81 | TAAR1 (0.50) | MAPTALDH1A1KMT2AESR1ESR2 | |
| SCHEMBL4399836 | 0.81 | TAAR1 (0.50) | MAPTALDH1A1KMT2AESR1ESR2 | |
| SCHEMBL113841 | 0.81 | TAAR1 (0.50) | MAPTALDH1A1KMT2AESR1ESR2 | |
| SCHEMBL10794218 | 0.78 | TSHR (0.43) | TSHRNPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1427689-B1 | 4-METHYL-4-ARYL-2-PENTANOLS WITH AN ANTIMICROBIAL ACTION, PRODUCTION AND USE THEREOF | SYMRISE GMBH & CO KG (DE) | 2009-12-30 | — | — | EP | disclosed |
| US-7119123-B2 | Antimicrobially active 4-methyl-4-aryl-2-pentanols, their preparation and use | SYMRISE GMBH & CO. KG (DE) | 2006-10-10 | — | — | US | disclosed |
| US-20040171698-A1 | Antimicrobially active 4-methyl-4-aryl-2-pentanols, their preparation and use | SYMRISE AG (DE) | 2004-09-02 | — | — | US | disclosed |
| EP-1427689-A1 | 4-METHYL-4-ARYL-2-PENTANOLS WITH AN ANTIMICROBIAL ACTION, PRODUCTION AND USE THEREOF | Symrise GmbH & Co. KG (DE) | 2004-06-16 | — | — | EP | disclosed |
| WO-2003024907-A1 | 4-METHYL-4-ARYL-2-PENTANOLS WITH AN ANTIMICROBIAL ACTION, PRODUCTION AND USE THEREOF | SYMRISE GMBH & CO. KG (DE) | 2003-03-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171698-A1 | Antimicrobially active 4-methyl-4-aryl-2-pentanols, their preparation and use | SRD5A2, HSD3B1, HSD17B2 | TSHR 302/4885NPC1 3251/4885MAPT 4809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.