Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | SHBG | P04278 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4399596 | 1.00 | CYP2C9 (0.44) | CYP2C9HIF1ACYP2D6PTPN5GRIN2D | |
| SCHEMBL4406531 | 1.00 | CYP2C9 (0.44) | CYP2C9HIF1ACYP2D6PTPN5GRIN2D | |
| SCHEMBL17275040 | 0.89 | SHBG (0.41) | CYP2C9HIF1AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL4402677 | 0.82 | TSHR (0.44) | SHBG | |
| SCHEMBL4402682 | 0.82 | TSHR (0.44) | SHBG | |
| SCHEMBL4402678 | 0.82 | TSHR (0.44) | SHBG | |
| SCHEMBL9887007 | 0.79 | CYP2D6 (0.47) | CYP2C9HIF1ACYP2D6PTPN5GRIN2D | |
| SCHEMBL4399836 | 0.79 | TAAR1 (0.50) | HIF1ACYP2D6GRIN2DGRIN1GRIN2A | |
| SCHEMBL4399833 | 0.79 | TAAR1 (0.50) | HIF1ACYP2D6GRIN2DGRIN1GRIN2A | |
| SCHEMBL113841 | 0.79 | TAAR1 (0.50) | HIF1ACYP2D6GRIN2DGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1427689-B1 | 4-METHYL-4-ARYL-2-PENTANOLS WITH AN ANTIMICROBIAL ACTION, PRODUCTION AND USE THEREOF | SYMRISE GMBH & CO KG (DE) | 2009-12-30 | — | — | EP | disclosed |
| US-7119123-B2 | Antimicrobially active 4-methyl-4-aryl-2-pentanols, their preparation and use | SYMRISE GMBH & CO. KG (DE) | 2006-10-10 | — | — | US | disclosed |
| US-20040171698-A1 | Antimicrobially active 4-methyl-4-aryl-2-pentanols, their preparation and use | SYMRISE AG (DE) | 2004-09-02 | — | — | US | disclosed |
| EP-1427689-A1 | 4-METHYL-4-ARYL-2-PENTANOLS WITH AN ANTIMICROBIAL ACTION, PRODUCTION AND USE THEREOF | Symrise GmbH & Co. KG (DE) | 2004-06-16 | — | — | EP | disclosed |
| WO-2003024907-A1 | 4-METHYL-4-ARYL-2-PENTANOLS WITH AN ANTIMICROBIAL ACTION, PRODUCTION AND USE THEREOF | SYMRISE GMBH & CO. KG (DE) | 2003-03-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171698-A1 | Antimicrobially active 4-methyl-4-aryl-2-pentanols, their preparation and use | SRD5A2, HSD3B1, HSD17B2 | CYP2C9 819/4885HIF1A 1570/4885CYP2D6 392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.