Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 4/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.45 |
| ▸ | VNN1 | O95497 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29421430 | 1.00 | KIF11 (0.50) | KIF11MRGPRX4GRM5CTSSTSHR | |
| Hydrochloric Acid SCHEMBL27358839 | 0.98 | MRGPRX4 (0.49) | KIF11MRGPRX4GRM5CTSSTSHR | |
| SCHEMBL28311752 | 0.92 | MRGPRX4 (0.46) | KIF11MRGPRX4GRM5CTSSTSHR | |
| SCHEMBL11092767 | 0.92 | KIF11 (0.63) | KIF11MRGPRX4GRM5CTSSTSHR | |
| Ammonia Solution, Strong SCHEMBL3947903 | 0.91 | MRGPRX4 (0.48) | KIF11MRGPRX4GRM5CTSSTSHR | |
| SCHEMBL27501231 | 0.89 | KIF11 (0.50) | KIF11MRGPRX4GRM5CTSSTSHR | |
| Formic Acid SCHEMBL29983913 | 0.89 | MRGPRX4 (0.47) | KIF11MRGPRX4GRM5CTSSL3MBTL1 | |
| SCHEMBL3836507 | 0.88 | CTSS (0.55) | KIF11MRGPRX4CTSSGRIN1GRIN2B | |
| Trifluoroacetic Acid SCHEMBL27502598 | 0.88 | FFAR1 (0.52) | L3MBTL1RXFP1PTPN5VNN1PTGDR2 | |
| SCHEMBL921315 | 0.84 | POLB (0.51) | KIF11MRGPRX4CTSSL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 464 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120129683-A | Azole derivatives as SHP2 inhibitors | IRBM股份公司 | 2025-06-10 | — | — | CN | claimed |
| CN-119905687-A | Water-based lithium ion battery electrolyte and preparation method thereof | 北京理工大学 | 2025-04-29 | — | — | CN | claimed |
| CN-119591582-A | Imide-based proteolytic modulators and related methods of use | 阿尔维纳斯运营股份有限公司 | 2025-03-11 | — | — | CN | claimed |
| CN-118398813-A | Positive electrode slurry, positive electrode sheet and secondary battery | 广东邦普循环科技有限公司 | 2024-07-26 | — | — | CN | claimed |
| US-20240243010-A1 | INHIBITOR FOR SELECTIVELY DEPOSITING THIN FILM AND METHOD FOR SELECTIVELY DEPOSITING THIN FILM | ADEKA CORPORATION (JP) | 2024-07-18 | — | — | US | claimed |
| CN-117790893-A | Electrolyte and lithium battery containing same | 蜂巢能源科技股份有限公司 | 2024-03-29 | — | — | CN | claimed |
| US-20230369039-A1 | METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2023-11-16 | — | — | US | claimed |
| CN-115010671-B | One-step synthesis method of 2-substituted quinazolinone | 江苏大学 | 2023-10-10 | — | — | CN | claimed |
| CN-113024530-B | Isatin-1, 2, 4-oxadiazole compound and preparation method and application thereof | 合肥工业大学 | 2023-07-18 | — | — | CN | claimed |
| CN-116003253-A | Preparation method of trifluoro-phenylpyrimidine intermediate 2- [3- (trifluoromethyl) phenyl ] dimethyl malonate | 上海试四化学品有限公司 | 2023-04-25 | — | — | CN | claimed |
| US-20020007086-A1 | Process for producing trifluoromethylbenzylamines | CENTRAL GLASS COMPANY, LIMITED (JP) | 2002-01-17 | — | — | US | claimed |
| CN-1277637-A | Method for preparing a substituted benzamide | RHODIA CHIMIE SA (FR) | 2000-12-20 | — | — | CN | claimed |
| US-5126497-A | Catalyst and process for the preparation of trifluoromethyltoluenes | OCCIDENTAL CHEMICAL CORPORATION (US) | 1992-06-30 | — | — | US | claimed |
| US-4822903-A | Fluorinated silica catalyst and preparation of aromatic/aliphatic nitriles in the presence thereof | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1989-04-18 | — | — | US | claimed |
| US-4438042-A | FROM AMIDES, FLUORINATE SILCEOUS CATALYSTS | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-03-20 | — | — | US | claimed |
| US-4436669-A | CYANATION, DECARBONYLATION, ACID CATALYSTS | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-03-13 | — | — | US | claimed |
| US-4144265-A | CHLOROMETHYLATION, CYANATION OF TRIFLUOROMETHYL BENZENE | THE DOW CHEMICAL COMPANY (US) | 1979-03-13 | — | — | US | claimed |
| US-4049712-A | Method for manufacturing hydrazodicarbonamide | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1977-09-20 | — | — | US | claimed |
| US-3984451-A | Method for preparing hydrazo-bis-acetonitriles | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1976-10-05 | — | — | US | claimed |
| US-3972874-A | Method for preparing symmetrical and unsymmetrical ketazines and mixtures thereof | PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1976-08-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020007086-A1 | Process for producing trifluoromethylbenzylamines | IDH1, INMT, TH | KIF11 2157/4885MRGPRX4 4534/4885GRM5 1889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.