Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 3/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PI4KA | P42356 | 2/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.40 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL986515 | 0.87 | FBP1 (0.49) | FBP1ADORA2AADORA1HSP90AA1HSP90AB1 | |
| SCHEMBL985294 | 0.86 | ADORA2A (0.51) | FBP1ADORA2AADORA1HSP90AA1HSP90AB1 | |
| SCHEMBL986513 | 0.86 | FBP1 (0.48) | FBP1ADORA2AADORA1HSP90AA1HSP90AB1 | |
| SCHEMBL986317 | 0.86 | FBP1 (0.48) | FBP1ADORA2AADORA1HSP90AA1HSP90AB1 | |
| SCHEMBL27772515 | 0.84 | ADORA2A (0.46) | FBP1ADORA2AADORA1HSP90AA1HSP90AB1 | |
| SCHEMBL4402903 | 0.82 | SLC28A2 (0.47) | FBP1ADORA2AADORA1MAPK1HSPA5 | |
| SCHEMBL4407310 | 0.77 | CCNA2 (0.41) | FBP1ADORA2AADORA1MAPK1PI4KA | |
| SCHEMBL16487432 | 0.70 | HSP90B1 (0.63) | HSP90AA1HSP90AB1 | |
| SCHEMBL16486933 | 0.69 | HSP90B1 (0.65) | HSP90AA1HSP90AB1ERBB2 | |
| SCHEMBL15089829 | 0.69 | TMIGD3 (0.43) | ADORA2AADORA1MAPK1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173609-B2 | Macrolides useful against inflammatory and allergic diseases | BASILEA PHARMACEUTICA AG (CH) | 2012-05-08 | — | — | US | disclosed |
| US-20100120706-A1 | Macrolides Useful Against Inflammatory and Allergic Diseases | BASILEA PHARMACEUTICA AG (CH) | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120706-A1 | Macrolides Useful Against Inflammatory and Allergic Diseases | HRH4, HRH2, IL4 | FBP1 3601/4885ADORA2A 1843/4885ADORA1 789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.