Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.41 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.40 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | CHKA | P35790 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 11/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 11/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.39 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.38 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL987270 | 0.87 | PI4KA (0.43) | CCNA2CDK2CCNA1CDK5DYRK1A | |
| SCHEMBL987269 | 0.86 | PI4KA (0.44) | CCNA2CDK2CCNA1CDK5DYRK1A | |
| SCHEMBL985566 | 0.86 | PI4KA (0.42) | CCNA2CDK2CCNA1CDK5DYRK1A | |
| SCHEMBL985660 | 0.86 | ADORA2A (0.51) | CCNA2CDK2CCNA1CDK5DYRK1A | |
| SCHEMBL4402903 | 0.84 | SLC28A2 (0.47) | ADORA2AADORA1FBP1HSPA5SLC28A2 | |
| SCHEMBL27772455 | 0.84 | PI4KA (0.43) | CCNA2CDK2CCNA1CDK5DYRK1A | |
| SCHEMBL982883 | 0.81 | HSPA5 (0.40) | CCNA2CDK2CCNA1CDK5DYRK1A | |
| SCHEMBL4402885 | 0.77 | FBP1 (0.46) | PI4KAPI4K2BPI4K2API4KBADORA2A | |
| SCHEMBL15089829 | 0.71 | TMIGD3 (0.43) | CCNA2CDK2CDK5CDK5R1ADORA2A | |
| SCHEMBL4025801 | 0.70 | FBP1 (0.48) | PI4KAPI4K2BPI4K2API4KBADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8173609-B2 | Macrolides useful against inflammatory and allergic diseases | BASILEA PHARMACEUTICA AG (CH) | 2012-05-08 | — | — | US | disclosed |
| US-20100120706-A1 | Macrolides Useful Against Inflammatory and Allergic Diseases | BASILEA PHARMACEUTICA AG (CH) | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120706-A1 | Macrolides Useful Against Inflammatory and Allergic Diseases | HRH4, HRH2, IL4 | CCNA2 2064/4885CDK2 3092/4885CCNA1 1896/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.