Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4404902 | 0.87 | ALOX5 (0.51) | ALOX5KMT2ATP53KIF11ACACB | |
| SCHEMBL2671133 | 0.87 | KDM4E (0.52) | ALOX5KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL4140245 | 0.83 | ALOX5 (0.47) | ALOX5KMT2ATP53ACACBACACA | |
| SCHEMBL18149140 | 0.75 | ALOX5 (0.58) | ALOX5TP53KDM4EHPGDLMNA | |
| SCHEMBL2671424 | 0.73 | ALOX5 (0.51) | ALOX5KMT2ATP53KIF11ACACB | |
| SCHEMBL18164723 | 0.73 | ALOX5 (0.51) | ALOX5TP53KDM4EFEN1 | |
| SCHEMBL31179919 | 0.72 | KIF11 (0.69) | KIF11ALDH1A1HPGDMAPTSLC2A1 | |
| SCHEMBL6009602 | 0.72 | KIF11 (0.69) | KIF11ALDH1A1HPGDMAPTSLC2A1 | |
| SCHEMBL13387223 | 0.71 | MAPT (0.53) | KIF11ALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL4400592 | 0.70 | ALOX5 (0.47) | ALOX5TP53KIF11ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012056372-A1 | N1/N2-LACTAM ACETYL-CoA CARBOXYLASE INHIBITORS | PFIZER INC. (US) | 2012-05-03 | — | — | WO | disclosed |