Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.34 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.34 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.34 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5380847 | 0.79 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL6585346 | 0.78 | KMT2A (0.52) | KMT2AMEN1LMNAKDM4EPABPC1 | |
| SCHEMBL982388 | 0.71 | KMT2A (0.61) | KMT2AMEN1LMNAKDM4EPABPC1 | |
| SCHEMBL4245330 | 0.71 | MEN1 (0.61) | KMT2AMEN1LMNAKDM4EPABPC1 | |
| SCHEMBL29786760 | 0.71 | KMT2A (0.61) | KMT2AMEN1LMNAKDM4EPABPC1 | |
| SCHEMBL5371344 | 0.71 | — | — | |
| SCHEMBL9700287 | 0.71 | KMT2A (0.48) | KMT2AMEN1LMNAHTTSMN1; SMN2 | |
| SCHEMBL2459975 | 0.71 | MEN1 (0.46) | KMT2AMEN1LMNAKDM4EPABPC1 | |
| SCHEMBL4199579 | 0.71 | PABPC1 (0.55) | KMT2AMEN1LMNAKDM4EPABPC1 | |
| SCHEMBL1251795 | 0.71 | MEN1 (0.50) | KMT2AMEN1LMNAKDM4EPABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170240521-A1 | PERIPHERALLY-ACTING CANNABINOID RECEPTOR AGONISTS FOR CHRONIC PAIN | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-08-24 | — | — | US | disclosed |
| US-9656981-B2 | Peripherally-acting cannabinoid receptor agonists for chronic pain | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-05-23 | — | — | US | disclosed |
| US-20150239859-A1 | PERIPHERALLY-ACTING CANNABINOID RECEPTOR AGONISTS FOR CHRONIC PAIN | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2015-08-27 | — | — | US | disclosed |
| US-8877422-B2 | Resist underlayer film composition and patterning process using the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2014-11-04 | — | — | US | disclosed |
| US-8877422-B2 | Resist underlayer film composition and patterning process using the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2014-11-04 | — | — | US | disclosed |
| US-20120108071-A1 | RESIST UNDERLAYER FILM COMPOSITION AND PATTERNING PROCESS USING THE SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2012-05-03 | — | — | US | disclosed |
| US-20120108071-A1 | RESIST UNDERLAYER FILM COMPOSITION AND PATTERNING PROCESS USING THE SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2012-05-03 | — | — | US | disclosed |
| EP-2447775-A1 | Resist underlayer film composition and patterning process using the same | Shin-Etsu Chemical Co., Ltd. (JP) | 2012-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239859-A1 | PERIPHERALLY-ACTING CANNABINOID RECEPTOR AGONISTS FOR CHRONIC PAIN | CNR2, CNR1, OPRL1 | KMT2A 4034/4885MEN1 4854/4885LMNA 3829/4885 |
| US-20170240521-A1 | PERIPHERALLY-ACTING CANNABINOID RECEPTOR AGONISTS FOR CHRONIC PAIN | CNR2, CNR1, OPRL1 | KMT2A 4034/4885MEN1 4854/4885LMNA 3829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.