Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 18/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12647582 | 0.83 | NOS1 (0.40) | ACACBCTNNB1WNT3A | |
| SCHEMBL12647973 | 0.83 | CTNNB1 (0.42) | CTNNB1WNT3A | |
| SCHEMBL4404559 | 0.82 | ACACB (0.46) | ACACB | |
| SCHEMBL551333 | 0.82 | ACACB (0.48) | ACACB | |
| SCHEMBL15687279 | 0.78 | ACACB (0.51) | ACACB | |
| SCHEMBL4136982 | 0.78 | ACACB (0.48) | ACACB | |
| SCHEMBL4402977 | 0.73 | ADORA2A (0.38) | — | |
| SCHEMBL4404815 | 0.73 | CTNNB1 (0.69) | CTNNB1WNT3A | |
| SCHEMBL14526756 | 0.71 | TRPA1 (0.42) | ACACB | |
| SCHEMBL5409329 | 0.71 | TRPA1 (0.44) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012056372-A1 | N1/N2-LACTAM ACETYL-CoA CARBOXYLASE INHIBITORS | PFIZER INC. (US) | 2012-05-03 | — | — | WO | disclosed |