Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MPL | P40238 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13458667 | 0.86 | MAP4K1 (0.46) | MAP4K1NPC1RAB9AL3MBTL1MEN1 | |
| SCHEMBL440405 | 0.85 | MEN1 (0.40) | RAB9AMEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL13458974 | 0.83 | TOP1 (0.46) | ADORA2AADORA1ESR1ESR2TOP1 | |
| SCHEMBL7610922 | 0.83 | ACACA (0.53) | NPC1L3MBTL1MAPK1SMN1; SMN2TDP1 | |
| SCHEMBL13458947 | 0.82 | ACACA (0.41) | MEN1MAPK1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL23942 | 0.81 | TOP1 (0.50) | RAB9AL3MBTL1MEN1MAPK1KMT2A | |
| SCHEMBL12112655 | 0.80 | ACACA (0.51) | L3MBTL1MEN1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL27752791 | 0.80 | TOP1 (0.49) | RAB9AL3MBTL1MEN1MAPK1KMT2A | |
| SCHEMBL1228342 | 0.79 | ENPP3 (0.45) | NPC1RAB9AMEN1PKMMAPK1 | |
| SCHEMBL3354791 | 0.79 | TOP1 (0.57) | L3MBTL1MAPK1ADORA2AADORA1TOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8436341-B2 | Electronic device including phenanthroline derivative | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-05-07 | — | — | US | disclosed |
| US-8436341-B2 | Electronic device including phenanthroline derivative | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-05-07 | — | — | US | disclosed |
| US-8309731-B2 | Electronic device including phenanthroline derivative | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-11-13 | — | — | US | disclosed |
| US-8309731-B2 | Electronic device including phenanthroline derivative | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-11-13 | — | — | US | disclosed |
| US-20120065402-A1 | ELECTRONIC DEVICE INCLUDING PHENANTHROLINE DERIVATIVE | E.I.DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-15 | — | — | US | disclosed |
| US-20120065402-A1 | ELECTRONIC DEVICE INCLUDING PHENANTHROLINE DERIVATIVE | E.I.DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-15 | — | — | US | disclosed |
| US-20100207108-A1 | ELECTRONIC DEVICE INCLUDING PHENANTHROLINE DERIVATIVE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-08-19 | — | — | US | disclosed |
| US-20100207108-A1 | ELECTRONIC DEVICE INCLUDING PHENANTHROLINE DERIVATIVE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-08-19 | — | — | US | disclosed |
| WO-2010075379-A2 | ELECTRONIC DEVICE INCLUDING PHENANTHROLINE DERIVATIVE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-07-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065402-A1 | ELECTRONIC DEVICE INCLUDING PHENANTHROLINE DERIVATIVE | PAH, AHR, TYR | MAP4K1 2713/4885NPC1 3238/4885RAB9A 359/4885 |
| US-20100207108-A1 | ELECTRONIC DEVICE INCLUDING PHENANTHROLINE DERIVATIVE | PAH, AHR, TYR | MAP4K1 2675/4885NPC1 3300/4885RAB9A 310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.