SCHEMBL1228342

SCHEMBL1228342

Cc1ccccc1-c1cc(-c2ccccc2)c2ccc3c(-c4ccccc4)cc(-c4ccccc4C)nc3c2n1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP3 O14638 1/20 0.45
ENPP1 P22413 1/20 0.45
KDM4E B2RXH2 4/20 0.44
ALDH1A1 P00352 5/20 0.41
TSHR P16473 3/20 0.41
RAB9A P51151 3/20 0.41
NPC1 O15118 2/20 0.41
HPGD P15428 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
TP53 P04637 1/20 0.41
HSD17B10 Q99714 1/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
MAPT P10636 2/20 0.41
LMNA P02545 1/20 0.41
RECQL P46063 1/20 0.41
ADORA3 P0DMS8 1/20 0.41
ADORA2A P29274 1/20 0.41
ADORA1 P30542 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1228210 0.97 ENPP3 (0.47) ENPP3ENPP1KDM4EALDH1A1TSHR
SCHEMBL29685232 0.94 CRHR1 (0.43) ENPP3ENPP1KDM4EALDH1A1TSHR
SCHEMBL1228190 0.90 PDE4A (0.41) ENPP3ENPP1KDM4EALDH1A1TSHR
SCHEMBL14560696 0.89 NUDT1 (0.44) ENPP3ENPP1KDM4EALDH1A1TSHR
SCHEMBL14560746 0.87 KDM4E (0.40) ENPP3ENPP1KDM4EALDH1A1TSHR
SCHEMBL13458717 0.86 ALDH1A1 (0.46) ENPP3ENPP1KDM4EALDH1A1TSHR
SCHEMBL5410630 0.86 KDM4E (0.39) ENPP3ENPP1KDM4EALDH1A1TSHR
SCHEMBL440405 0.85 MEN1 (0.40) KDM4EALDH1A1RAB9AHPGDSMN1; SMN2
SCHEMBL14560695 0.85 ALDH1A1 (0.48) KDM4EALDH1A1TSHRRAB9ANPC1
SCHEMBL14560723 0.85 ALDH1A1 (0.48) KDM4EALDH1A1HPGDNPSR1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2299508-A2 Organic photosensitive optoelectronic device having a phenanthroline exciton blocking layer The Trustees of Princeton University (US) 2011-03-23 EP claimed
CN-101076904-B Organic photosensitive optoelectronic device with phenanthroline exciton barrier-layer UNIV PRINCETON 2011-01-19 CN claimed
EP-2299508-A2 Organic photosensitive optoelectronic device having a phenanthroline exciton blocking layer The Trustees of Princeton University (US) 2011-03-23 EP disclosed
US-7893352-B2 Organic photosensitive optoelectronic device having a phenanthroline exciton blocking layer THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2011-02-22 US disclosed
CN-101076904-B Organic photosensitive optoelectronic device with phenanthroline exciton barrier-layer UNIV PRINCETON 2011-01-19 CN disclosed
EP-1097981-B1 Organic electroluminescent device SONY CORP (JP) 2010-04-14 EP disclosed
CN-101076904-A Organic photosensitive optoelectronic device with phenanthroline exciton barrier-layer UNIV PRINCETON (US) 2007-11-21 CN disclosed
EP-1815544-A2 ORGANIC PHOTOSENSITIVE OPTOELECTRONIC DEVICE HAVING A PHENANTHROLINE EXCITON BLOCKING LAYER The Trustees of Princeton University (US) 2007-08-08 EP disclosed
US-7186469-B2 Bathophenanthroline compound and EL device SONY CORPORATION (JP) 2007-03-06 US disclosed
US-7186469-B2 Bathophenanthroline compound and EL device SONY CORPORATION (JP) 2007-03-06 US disclosed
US-7186469-B2 Bathophenanthroline compound and EL device SONY CORPORATION (JP) 2007-03-06 US disclosed
WO-2006086040-A2 ORGANIC PHOTOSENSITIVE OPTOELECTRONIC DEVICE HAVING A PHENANTHROLINE EXCITON BLOCKING LAYER THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2006-08-17 WO disclosed
US-20060138453-A1 Organic photosensitive optoelectronic device having a phenanthroline exciton blocking layer ENTIRE INTEREST 2006-06-29 US disclosed
US-6972334-B1 Bathophenathroline compound and process for preparing same SONY CORPORATION (JP) 2005-12-06 US disclosed
US-20050154208-A1 Device utilizing bathophenanthroline compound and process for preparing same SHIBANUMA TETSUO (JP) 2005-07-14 US disclosed
EP-1097980-A2 Bathophenanthroline compound and process for preparing same SONY CORPORATION (JP) 2001-05-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050154208-A1 Device utilizing bathophenanthroline compound and process for preparing same BZW1, BZW2, AHR ENPP3 2302/4885ENPP1 742/4885KDM4E 3292/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.