Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | S100A4 | P26447 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5635241 | 0.81 | MEN1 (0.47) | MEN1KMT2AACHEPARP1PARP10 | |
| SCHEMBL11878033 | 0.77 | ACHE (0.50) | MEN1KMT2AACHEALDH1A1S100A4 | |
| SCHEMBL254906 | 0.76 | MAOA (0.47) | MEN1KMT2AACHEPARP1CA1 | |
| SCHEMBL1853908 | 0.76 | PIM1 (0.39) | MEN1KMT2AACHEPARP10PARP11 | |
| SCHEMBL9171936 | 0.76 | MAPT (0.41) | MEN1KMT2AACHEDAOALDH1A1 | |
| SCHEMBL18162627 | 0.76 | NOTUM (0.48) | MEN1KMT2AACHECA1CA2 | |
| SCHEMBL30908525 | 0.76 | PIM1 (0.39) | MEN1KMT2AACHEPARP10PARP11 | |
| Hydrochloric Acid SCHEMBL10513970 | 0.74 | MAPT (0.40) | MEN1KMT2AACHEDAOALDH1A1 | |
| SCHEMBL15039690 | 0.73 | ACHE (0.33) | MEN1KMT2AACHEALDH1A1KDM4E | |
| SCHEMBL20022731 | 0.72 | CES1 (0.41) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016165007-A1 | INHIBITORS OF ESTROGEN RECEPTOR ALPHA AND THEIR USE AS THERAPEUTICS FOR CANCER | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2016-10-20 | — | — | WO | disclosed |
| EP-2261270-B1 | Polymer, producing method thereof, and photorefractive composition | NITTO DENKO CORP (JP) | 2012-05-09 | — | — | EP | disclosed |
| WO-2003057161-A2 | BENZOTHIENO [3,2-c]PYRAZOLYL AND BENZOFURANO [3,2-c] PYRAZOLYL COMPOUNDS, THEIR USE IN DISEASES ASSOCIATED WITH THE 5-HT2C RECEPTOR AND INTERMEDIATE COMPOUNDS THEREOF | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-07-17 | — | — | WO | disclosed |