Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | TPSAB1 | Q15661 | 13/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4404040 | 0.85 | CYP3A4 (0.49) | CYP3A4CYP2D6KCNH2TPSAB1 | |
| Trifluoroacetic Acid SCHEMBL4398472 | 0.84 | TPSAB1 (0.49) | CYP3A4CYP2D6KCNH2TPSAB1 | |
| Trifluoroacetic Acid SCHEMBL4398549 | 0.84 | TPSAB1 (0.52) | TPSAB1 | |
| SCHEMBL7151703 | 0.84 | TPSAB1 (0.46) | CYP3A4CYP2D6KCNH2TPSAB1 | |
| Trifluoroacetic Acid SCHEMBL6317047 | 0.82 | TPSAB1 (0.51) | TPSAB1 | |
| Trifluoroacetic Acid SCHEMBL4399054 | 0.81 | TPSAB1 (0.49) | TPSAB1 | |
| Trifluoroacetic Acid SCHEMBL1381956 | 0.81 | TPSAB1 (0.50) | CYP3A4CYP2D6KCNH2TPSAB1 | |
| SCHEMBL4403180 | 0.73 | CYP3A4 (0.49) | CYP3A4CYP2D6KCNH2TPSAB1 | |
| SCHEMBL4404783 | 0.71 | CYP3A4 (0.47) | CYP3A4CYP2D6KCNH2TPSAB1 | |
| SCHEMBL4411516 | 0.70 | CYP3A4 (0.51) | CYP3A4CYP2D6KCNH2TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1296972-B1 | ARYLMETHYLAMINE DERIVATIVES FOR USE AS TRYPTASE INHIBITORS | AVENTIS PHARMA INC (US) | 2009-12-23 | — | — | EP | disclosed |
| US-6977263-B2 | Chemical compounds | AVENTIS PHARMACEUTICALS INC. (US) | 2005-12-20 | — | — | US | disclosed |
| US-20050228018-A1 | Chemical compounds | AVENTIS PHARMACEUTICALS INC. (US) | 2005-10-13 | — | — | US | disclosed |
| US-20030187020-A1 | Chemical compounds | AVENTISUB LLC | 2003-10-02 | — | — | US | disclosed |
| EP-1296972-A1 | ARYLMETHYLAMINE DERIVATIVES FOR USE AS TRYPTASE INHIBITORS | Aventis Pharmaceuticals Inc. (US) | 2003-04-02 | — | — | EP | disclosed |
| WO-2001090101-A1 | ARYLMETHYLAMINE DERIVATIVES FOR USE AS TRYPTASE INHIBITORS | AVENTIS PHARMACEUTICALS INC. (US) | 2001-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050228018-A1 | Chemical compounds | CMA1, TPSB2, TPSG1 | CYP3A4 1205/4885CYP2D6 1526/4885KCNH2 2745/4885 |
| US-20030187020-A1 | Chemical compounds | CMA1, TPSB2, TPSG1 | CYP3A4 1205/4885CYP2D6 1526/4885KCNH2 2745/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.