Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3068225 | 0.81 | CA2 (0.52) | CA2CA4CA5AALDH1A1MEN1 | |
| SCHEMBL3067334 | 0.77 | CA2 (0.48) | CA2CA4CA5AALDH1A1MEN1 | |
| SCHEMBL361668 | 0.73 | CA2 (0.43) | CA2CA4CA5AALDH1A1MEN1 | |
| SCHEMBL22471970 | 0.73 | CA2 (0.58) | CA2CA4CA5AALDH1A1MEN1 | |
| SCHEMBL31574395 | 0.73 | CA2 (0.58) | CA2CA4CA5AALDH1A1MEN1 | |
| SCHEMBL2932036 | 0.72 | CA2 (0.47) | CA2CA4CA5AALDH1A1MEN1 | |
| SCHEMBL10710709 | 0.71 | CA2 (0.41) | CA2CA4CA5AALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL996153 | 0.71 | CA2 (0.41) | CA2CA4CA5AALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL2582115 | 0.71 | CA2 (0.41) | CA2CA4CA5AALDH1A1MEN1 | |
| Water SCHEMBL7532602 | 0.71 | CA2 (0.41) | CA2CA4CA5AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152464-A1 | SYNTHETIC PROCESS FOR AMINOCYCLOHEXYL ETHER COMPOUNDS | CARDIOME PHARMA CORP. (CA) | 2010-06-17 | — | — | US | claimed |
| EP-1828099-A1 | SYNTHETIC PROCESS FOR AMINOCYCLOHEXYL ETHER COMPOUNDS | Cardimone Pharma Corporation (CA) | 2007-09-05 | — | — | EP | claimed |
| WO-2006088525-A1 | SYNTHETIC PROCESS FOR AMINOCYCLOHEXYL ETHER COMPOUNDS | CARDIOME PHARMA CORP. (CA) | 2006-08-24 | — | — | WO | claimed |
| US-20060094880-A9 | Synthetic process for trans-aminocyclohexyl ether compounds | BARRETT ANTHONY G M | 2006-05-04 | — | — | US | claimed |
| WO-2005016242-A2 | SYNTHETIC PROCESS FOR TRANS-AMINOCYCLOHEXYL ETHER COMPOUNDS | CARDIOME PHARMA CORP. (CA) | 2005-02-24 | — | — | WO | claimed |
| US-20050038256-A1 | Synthetic process for trans-aminocyclohexyl ether compounds | CARDIOME PHARMA CORP. (CA) | 2005-02-17 | — | — | US | claimed |
| US-20230131867-A1 | TRITERPENE SAPONINS, METHODS OF SYNTHESIS AND USES THEREOF | SLOAN KETTERING INST CANCER RES (US) | 2023-04-27 | — | — | US | disclosed |
| EP-3357931-B1 | METHODS OF SYNTHESIS OF TRITERPENE PROSAPOGENINS AND TRITERPENE SAPONINS | SLOAN KETTERING INST CANCER RES (US) | 2020-07-22 | — | — | EP | disclosed |
| EP-3357931-A1 | METHODS OF SYNTHESIS OF TRITERPENE PROSAPOGENINS AND TRITERPENE SAPONINS | Sloan Kettering Institute For Cancer Research (US) | 2018-08-08 | — | — | EP | disclosed |
| EP-2280987-B1 | TRITERPENE SAPONINS, METHODS OF SYNTHESIS, AND USES THEREOF | SLOAN KETTERING INST CANCER RES (US) | 2018-05-23 | — | — | EP | disclosed |
| US-20170283450-A1 | TRITERPENE SAPONINS, METHODS OF SYNTHESIS AND USES THEREOF | MEMORIAL SLOAN-KETTERING INST FOR CANCER RES (US) | 2017-10-05 | — | — | US | disclosed |
| US-9718850-B2 | Triterpene saponins, methods of synthesis and uses thereof | MEMORIAL SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2017-08-01 | — | — | US | disclosed |
| US-9586899-B2 | Synthetic process for aminocyclohexyl ether compounds | CARDIOME PHARMA CORP. (CA) | 2017-03-07 | — | — | US | disclosed |
| WO-2006138673-A2 | SYNTHETIC PROCESSES FOR THE PREPARATION OF AMINOCYCLOHEXYL ETHER COMPOUNDS | CARDIOME PHARMA CORP. (CA) | 2006-12-28 | — | — | WO | disclosed |
| WO-2006088525-A1 | SYNTHETIC PROCESS FOR AMINOCYCLOHEXYL ETHER COMPOUNDS | CARDIOME PHARMA CORP. (CA) | 2006-08-24 | — | — | WO | disclosed |
| US-20060094880-A9 | Synthetic process for trans-aminocyclohexyl ether compounds | BARRETT ANTHONY G M | 2006-05-04 | — | — | US | disclosed |
| WO-2005016242-A2 | SYNTHETIC PROCESS FOR TRANS-AMINOCYCLOHEXYL ETHER COMPOUNDS | CARDIOME PHARMA CORP. (CA) | 2005-02-24 | — | — | WO | disclosed |
| US-20050038256-A1 | Synthetic process for trans-aminocyclohexyl ether compounds | CARDIOME PHARMA CORP. (CA) | 2005-02-17 | — | — | US | disclosed |
| US-6084081-A | Lewis X derivatives | DAIKIN INDUSTRIES, LTD. (JP) | 2000-07-04 | — | — | US | disclosed |
| EP-0930315-A1 | LEWIS X DERIVATIVES | DAIKIN INDUSTRIES, LTD. (JP) | 1999-07-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094880-A9 | Synthetic process for trans-aminocyclohexyl ether compounds | AKR1C3, CBR1, CBR3 | CA2 1395/4885CA4 1149/4885CA5A 1141/4885 |
| US-20230131867-A1 | TRITERPENE SAPONINS, METHODS OF SYNTHESIS AND USES THEREOF | LSS, CYP51A1, TLR7 | CA2 3692/4885CA4 1704/4885CA5A 2556/4885 |
| US-20050038256-A1 | Synthetic process for trans-aminocyclohexyl ether compounds | AKR1C3, CBR1, CBR3 | CA2 1395/4885CA4 1149/4885CA5A 1141/4885 |
| US-20100152464-A1 | SYNTHETIC PROCESS FOR AMINOCYCLOHEXYL ETHER COMPOUNDS | DDC, PAICS, CYP4F2 | CA2 4608/4885CA4 3349/4885CA5A 3253/4885 |
| US-20170283450-A1 | TRITERPENE SAPONINS, METHODS OF SYNTHESIS AND USES THEREOF | LSS, CYP51A1, TLR7 | CA2 3692/4885CA4 1704/4885CA5A 2556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.