Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.41 |
| ▸ | ESR1 known ✓ | P03372 | 3/20 | 0.36 |
| ▸ | ESR2 known ✓ | Q92731 | 2/20 | 0.36 |
| ▸ | GAA known ✓ | P10253 | 2/20 | 0.35 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.33 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.33 |
| ▸ | PTGS2 known ✓ | P35354 | 1/20 | 0.33 |
| ▸ | HTR2B known ✓ | P41595 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL996153 | 1.00 | CA2 (0.41) | CA2CA4CA5AESR1ESR2 | |
| SCHEMBL361668 | 0.97 | CA2 (0.43) | CA2CA4CA5AESR1ESR2 | |
| Bromide SCHEMBL2185231 | 0.93 | CA2 (0.41) | CA2CA4CA5AESR1ESR2 | |
| Fluoride SCHEMBL11191593 | 0.93 | CA2 (0.41) | CA2CA4CA5AESR1ESR2 | |
| Iodide SCHEMBL27336456 | 0.93 | CA2 (0.41) | CA2CA4CA5AESR1ESR2 | |
| SCHEMBL6316218 | 0.93 | CA2 (0.41) | CA2CA4CA5AESR1ESR2 | |
| Water SCHEMBL7532602 | 0.93 | CA2 (0.41) | CA2CA4CA5AESR1ESR2 | |
| SCHEMBL10710709 | 0.93 | CA2 (0.41) | CA2CA4CA5AESR1ESR2 | |
| Iodide SCHEMBL3694471 | 0.93 | CA2 (0.41) | CA2CA4CA5AESR1ESR2 | |
| Carbon Monoxide SCHEMBL10708053 | 0.89 | CA2 (0.40) | CA2CA4CA5AESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12600816-B2 | Alkylene oxide polymerization using aluminum compounds and phosphorus-nitrogen bases | DOW GLOBAL TECHNOLOGIES LLC (US) | 2026-04-14 | — | — | US | disclosed |
| US-20230092304-A1 | ALKYLENE OXIDE POLYMERIZATION USING ALUMINUM COMPOUNDS AND PHOSPHORUS-NITROGEN BASES | DOW GLOBAL TECHNOLOGIES LLC | 2023-03-23 | — | — | US | disclosed |
| EP-4097169-A1 | ALKYLENE OXIDE POLYMERIZATION USING ALUMINUM COMPOUNDS AND PHOSPHORUS-NITROGEN BASES | Dow Global Technologies LLC (US) | 2022-12-07 | — | — | EP | disclosed |
| CN-114787172-A | Olefin oxidative cracking process using halooxyderoxymetalate as catalyst | 德美特 | 2022-07-22 | — | — | CN | disclosed |
| CN-106243336-B | Poly (monothiocarbonate) containing crystals and preparation method thereof | 浙江大学 | 2021-04-27 | — | — | CN | disclosed |
| CN-106536045-B | Catalyst and process for preparing same | IP2IPO 创新有限公司 | 2020-02-07 | — | — | CN | disclosed |
| CN-107459639-A | A kind of catalyst system for preparing aviation polyether material | 中国民用航空总局第二研究所 | 2017-12-12 | — | — | CN | disclosed |
| CN-102197062-B | Aliphatic polycarbonate quench method | NOVOMER INC | 2015-07-08 | — | — | CN | disclosed |
| CN-104193980-A | POLYMERS OF ETHYLENE OXIDE AND CARBON DIOXIDE | UNIV CORNELL | 2014-12-10 | — | — | CN | disclosed |
| EP-2566852-A1 | CARBON SUPPORTED TETRAAMIDO MACROCYCLIC LIGAND CATALYTIC ACTIVATORS AND METHODS FOR MAKING THE SAME | Carnegie Mellon University (US) | 2013-03-13 | — | — | EP | disclosed |
| WO-2011137190-A1 | CARBON SUPPORTED TETRAAMIDO MACROCYCLIC LIGAND CATALYTIC ACTIVATORS AND METHODS FOR MAKING THE SAME | CARNEGIE MELLON UNIVERSITY (US) | 2011-11-03 | — | — | WO | disclosed |
| CN-1639113-B | Method for producing 2-chloromethylphenyl acetic acid derivatives | BASF AG | 2011-06-01 | — | — | CN | disclosed |
| CN-102015826-A | Polymers of ethylene oxide and carbon dioxide | UNIV CORNELL | 2011-04-13 | — | — | CN | disclosed |
| CN-1295017-C | Modified acidic ion-exchange resin and method for preparing bisphenol | MITSUI CHEMICALS INC (JP) | 2007-01-17 | — | — | CN | disclosed |
| CN-1639113-A | Method for producing 2-chloromethylphenyl acetic acid derivatives | BASF AG (DE) | 2005-07-13 | — | — | CN | disclosed |
| CN-1613561-A | Modified acidic ion-exchange resin and method for preparing bisphenol | MITSUI CHEMICALS INC (JP) | 2005-05-11 | — | — | CN | disclosed |
| US-4320064-A | HYDROGENATION CATALYSTS | UNION CARBIDE CORPORATION (US) | 1982-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12600816-B2 | Alkylene oxide polymerization using aluminum compounds and phosphorus-nitrogen bases | PTEN, PHOSPHO1, ACP1 | CA2 283/4885ESR1 1608/4885ESR2 2828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.