Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4405709 | 0.88 | KMT2A (0.41) | ALDH1A1HSD17B10KMT2AMEN1CYP2C19 | |
| SCHEMBL4407954 | 0.86 | SLC9A1 (0.40) | KMT2AMEN1SLC9A1 | |
| SCHEMBL4408634 | 0.85 | SLC9A1 (0.41) | KMT2AMEN1SLC9A1 | |
| SCHEMBL4407149 | 0.83 | ALDH1A1 (0.45) | ALDH1A1HSD17B10KMT2AMEN1POLB | |
| SCHEMBL24142447 | 0.82 | MAPK1 (0.36) | CYP1A2ALDH1A1KMT2AMEN1POLB | |
| SCHEMBL95314 | 0.82 | MAPK1 (0.36) | CYP1A2ALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL12141919 | 0.80 | MAPK1 (0.42) | ALDH1A1HSD17B10KMT2AMEN1POLB | |
| SCHEMBL10197492 | 0.79 | UBE2M (0.40) | ALDH1A1HSD17B10KMT2AMAPK1LMNA | |
| SCHEMBL24142417 | 0.79 | MAPK1 (0.35) | ALDH1A1KMT2AMAPK1LMNA | |
| SCHEMBL4544043 | 0.77 | CNR2 (0.41) | ALDH1A1KMT2AMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024020458-A1 | METHOD OF TREATING ORGAN DISEASES OR DISORDERS WITH ASK1 INHIBITORS | Seal Rock Therapeutics, Inc. (US) | 2024-01-25 | — | — | WO | disclosed |
| US-11641858-B2 | Agricultural chemicals | REDAG CROP PROTECTION LTD. (GB) | 2023-05-09 | — | — | US | disclosed |
| US-11566023-B2 | Oxazolidinone compounds, liposome compositions comprising oxazolidinone compounds and method of use thereof | AKAGERA MEDICINES, INC. (US) | 2023-01-31 | — | — | US | disclosed |
| US-11241013-B2 | Benzimidazole compounds as agricultural chemicals | REDAG CROP PROT LTD (GB) | 2022-02-08 | — | — | US | disclosed |
| US-20210204547-A1 | BENZIMIDAZOLE COMPOUNDS AS AGRICULTURAL CHEMICALS | REDAG CROP PROT LTD (GB) | 2021-07-08 | — | — | US | disclosed |
| US-20210087167-A1 | ASK1 INHIBITOR COMPOUNDS AND USES THEREOF | Seal Rock Therapeutics, Inc. | 2021-03-25 | — | — | US | disclosed |
| US-20200323209-A1 | AGRICULTURAL CHEMICALS | REDAG CROP PROTECTION LTD. (GB) | 2020-10-15 | — | — | US | disclosed |
| EP-1859782-B1 | Composition for coloring and/or lightening human hair comprising tetrazoles | HENKEL AG & CO KGAA (DE) | 2009-12-30 | — | — | EP | disclosed |
| EP-1859782-A1 | Composition for coloring and/or lightening human hair comprising tetrazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |
| US-7160886-B2 | Acylated piperazine derivatives as melanocortin-4 receptor agonists | MERCK & CO., INC. (US) | 2007-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210087167-A1 | ASK1 INHIBITOR COMPOUNDS AND USES THEREOF | ATF1, MAP3K1, ROCK1 | CYP1A2 2385/4885ALDH1A1 776/4885HSD17B10 900/4885 |
| US-20200323209-A1 | AGRICULTURAL CHEMICALS | DDT, CYP4X1, CYP1A2 | CYP1A2 3/4885ALDH1A1 365/4885HSD17B10 199/4885 |
| US-11241013-B2 | Benzimidazole compounds as agricultural chemicals | CYP3A4, CYP2C8, CYP2E1 | CYP1A2 14/4885ALDH1A1 561/4885HSD17B10 726/4885 |
| US-11641858-B2 | Agricultural chemicals | DDT, CYP4X1, CYP1A2 | CYP1A2 3/4885ALDH1A1 365/4885HSD17B10 199/4885 |
| US-11566023-B2 | Oxazolidinone compounds, liposome compositions comprising oxazolidinone compounds and method of use thereof | OXA1L, THPO, TBCD | CYP1A2 1270/4885ALDH1A1 2027/4885HSD17B10 602/4885 |
| US-20210204547-A1 | BENZIMIDAZOLE COMPOUNDS AS AGRICULTURAL CHEMICALS | CYP3A4, CYP2C8, CYP2E1 | CYP1A2 14/4885ALDH1A1 561/4885HSD17B10 726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.