SCHEMBL4405448

SCHEMBL4405448

COc1cc2c(cc1O)OCC(c1ccc(O)cc1)C2

nearest known ligand 0.72

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 6/20 0.72
ALOX12 P18054 6/20 0.72
ALOX15B O15296 3/20 0.72
ESR1 P03372 1/20 0.62
ESR2 Q92731 1/20 0.62
TTR P02766 1/20 0.62
CYP3A4 P08684 2/20 0.42
CYP2D6 P10635 1/20 0.42
PTPN1 P18031 2/20 0.42
ALOX5 P09917 1/20 0.42
PPARG P37231 1/20 0.42
PPARD Q03181 1/20 0.42
HTR1A P08908 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30912709 1.00 ALOX15 (0.72) ALOX15ALOX12ALOX15BESR1ESR2
SCHEMBL30933011 1.00 ALOX15 (0.72) ALOX15ALOX12ALOX15BESR1ESR2
SCHEMBL571151 0.84 ALOX12 (1.00) ALOX15ALOX12ALOX15BESR1ESR2
SCHEMBL17963715 0.82 ESR1 (0.67) ALOX15ALOX12ALOX15BESR1ESR2
SCHEMBL30932995 0.82 ESR1 (0.67) ALOX15ALOX12ALOX15BESR1ESR2
SCHEMBL30851574 0.82 ESR1 (0.67) ALOX15ALOX12ALOX15BESR1ESR2
Glycitein SCHEMBL4653829 0.82 HDAC6 (0.67) ALOX15ALOX12ALOX15BESR1ESR2
SCHEMBL8118137 0.82 ALOX15 (0.72) ALOX15ALOX12ALOX15BESR1ESR2
SCHEMBL28900364 0.81 ALOX15 (0.54) ALOX15ALOX12ALOX15BESR1ESR2
SCHEMBL10562731 0.81 ALOX15 (1.00) ALOX15ALOX12ALOX15BESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090312408-A1 ISOFLAVAN AND ISOFLAVENE COMPOUNDS AND THEIR USE AS ANGIOGENESIS INHIBITORS ADLERCREUTZ HERMAN 2009-12-17 US claimed
EP-1991538-A1 ISOFLAVAN AND ISOFLAVENE COMPOUNDS AND THEIR USE AS ANGIOGENESIS INHIBITORS Adlercreutz, Herman (FI) 2008-11-19 EP claimed
WO-2007096471-A1 ISOFLAVAN AND ISOFLAVENE COMPOUNDS AND THEIR USE AS ANGIOGENESIS INHIBITORS ADLERCREUTZ HERMAN (FI) 2007-08-30 WO claimed
US-20070203227-A1 Isoflavan and isoflavene compounds and their use as angiogenesis inhibitors ADLERCREUTZ HERMAN 2007-08-30 US claimed
US-20250051551-A1 IMPROVED POLYMER COMPOSITES WARNER BABCOCK INSTITUTE FOR GREEN CHEMISTRY, LLC (US) 2025-02-13 US disclosed
US-12163004-B2 Polymer composites WARNER BABCOCK INSTITUTE FOR GREEN CHEMISTRY, LLC (US) 2024-12-10 US disclosed
US-20240355451-A1 METHODS FOR IMPROVING GUT MICROBIOTA DIVERSITY NESTLE SA (CH) 2024-10-24 US disclosed
EP-4391834-A1 METHODS FOR IMPROVING GUT MICROBIOTA DIVERSITY Société des Produits Nestlé S.A. (CH) 2024-07-03 EP disclosed
US-20240101791-A1 POLYMER COMPOSITES WARNER BABCOCK INSTITUTE FOR GREEN CHEMISTRY, LLC (US) 2024-03-28 US disclosed
WO-2024059282-A1 IMPROVED POLYMER COMPOSITES WARNER BABCOCK INSTITUTE FOR GREEN CHEMISTRY, LLC (US) 2024-03-21 WO disclosed
US-20230255989-A1 GLYCAN COMPOSITIONS AND USES THEREOF DSM NUTRITIONAL PRODUCTS LLC (US) 2023-08-17 US disclosed
WO-2023025722-A1 METHODS FOR IMPROVING GUT MICROBIOTA DIVERSITY Société des Produits Nestlé S.A. (CH) 2023-03-02 WO disclosed
US-9492473-B2 Glycan therapeutics and related methods thereof KALEIDO BIOSCIENCES, INC. (US) 2016-11-15 US disclosed
EP-3071235-A1 GLYCAN THERAPEUTICS AND RELATED METHODS THEREOF Kaleido Biosciences, Inc. (US) 2016-09-28 EP disclosed
WO-2016122889-A1 GLYCAN THERAPEUTICS AND RELATED METHODS THEREOF KALEIDO BIOSCIENCES, INC. (US) 2016-08-04 WO disclosed
US-20160213702-A1 GLYCAN THERAPEUTICS AND RELATED METHODS THEREOF KALEIDO BIOSCIENCES, INC. (US) 2016-07-28 US disclosed
US-20090312408-A1 ISOFLAVAN AND ISOFLAVENE COMPOUNDS AND THEIR USE AS ANGIOGENESIS INHIBITORS ADLERCREUTZ HERMAN 2009-12-17 US disclosed
EP-1991538-A1 ISOFLAVAN AND ISOFLAVENE COMPOUNDS AND THEIR USE AS ANGIOGENESIS INHIBITORS Adlercreutz, Herman (FI) 2008-11-19 EP disclosed
WO-2007096471-A1 ISOFLAVAN AND ISOFLAVENE COMPOUNDS AND THEIR USE AS ANGIOGENESIS INHIBITORS ADLERCREUTZ HERMAN (FI) 2007-08-30 WO disclosed
US-20070203227-A1 Isoflavan and isoflavene compounds and their use as angiogenesis inhibitors ADLERCREUTZ HERMAN 2007-08-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070203227-A1 Isoflavan and isoflavene compounds and their use as angiogenesis inhibitors VEGFA, FLT1, FLT4 ALOX15 1341/4885ALOX12 1178/4885ALOX15B 1494/4885
US-20090312408-A1 ISOFLAVAN AND ISOFLAVENE COMPOUNDS AND THEIR USE AS ANGIOGENESIS INHIBITORS VEGFA, PGF, HIF1AN ALOX15 1855/4885ALOX12 1763/4885ALOX15B 2049/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.