Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.32 |
| ▸ | UNG | P13051 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.30 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29521419 | 0.89 | ALDH1A1 (0.44) | ALDH1A1MEN1GAAMAPTHPGD | |
| SCHEMBL4408078 | 0.85 | ALDH1A1 (0.36) | ALDH1A1MEN1GAAMAPTHPGD | |
| SCHEMBL4403393 | 0.82 | CYP2A6 (0.37) | ALDH1A1MEN1GAAMAPTHPGD | |
| SCHEMBL4402558 | 0.82 | CYP2A6 (0.37) | ALDH1A1MEN1GAAMAPTHPGD | |
| SCHEMBL28029104 | 0.81 | ALDH1A1 (0.36) | ALDH1A1MAPTTDP1 | |
| SCHEMBL2856444 | 0.81 | ALDH1A1 (0.38) | ALDH1A1MEN1GAAMAPTHPGD | |
| SCHEMBL4745707 | 0.75 | CYP2A6 (0.37) | ALDH1A1KDM4EPTGS2RAB9AHSD17B10 | |
| SCHEMBL2525091 | 0.75 | FFAR4 (0.31) | — | |
| SCHEMBL6784505 | 0.74 | ALDH1A1 (0.46) | ALDH1A1MEN1GAAMAPTHPGD | |
| SCHEMBL4448971 | 0.74 | CYP2A6 (0.36) | ALDH1A1KDM4EPTGS2RAB9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108264476-A | A kind of anticancer drug Ai Li replaces the preparation method of Buddhist nun's intermediate | 董丹丹 | 2018-07-10 | — | — | CN | claimed |
| CN-107987056-A | A kind of new anaplastic lymphoma kinase (ALK) inhibitor Ai Li replaces the preparation method of Buddhist nun | 董丹丹 | 2018-05-04 | — | — | CN | claimed |
| CN-108264476-A | A kind of anticancer drug Ai Li replaces the preparation method of Buddhist nun's intermediate | 董丹丹 | 2018-07-10 | — | — | CN | disclosed |
| CN-107987056-A | A kind of new anaplastic lymphoma kinase (ALK) inhibitor Ai Li replaces the preparation method of Buddhist nun | 董丹丹 | 2018-05-04 | — | — | CN | disclosed |
| US-8877422-B2 | Resist underlayer film composition and patterning process using the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2014-11-04 | — | — | US | disclosed |
| US-8877422-B2 | Resist underlayer film composition and patterning process using the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2014-11-04 | — | — | US | disclosed |
| EP-2447775-B1 | Resist underlayer film composition and patterning process using the same | SHINETSU CHEMICAL CO (JP) | 2013-05-29 | — | — | EP | disclosed |
| US-20120108071-A1 | RESIST UNDERLAYER FILM COMPOSITION AND PATTERNING PROCESS USING THE SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2012-05-03 | — | — | US | disclosed |
| US-20120108071-A1 | RESIST UNDERLAYER FILM COMPOSITION AND PATTERNING PROCESS USING THE SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2012-05-03 | — | — | US | disclosed |
| EP-2447775-A1 | Resist underlayer film composition and patterning process using the same | Shin-Etsu Chemical Co., Ltd. (JP) | 2012-05-02 | — | — | EP | disclosed |