Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 7/20 | 0.38 |
| ▸ | MAOB | P27338 | 4/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 3/20 | 0.36 |
| ▸ | HTR7 | P34969 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | DRD3 | P35462 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4396426 | 0.94 | BDKRB1 (0.37) | SOS1MAOBMAOAKDM4EALDH1A1 | |
| SCHEMBL4405941 | 0.94 | HTR1A (0.36) | SOS1MAOBMAOAHTR1AHTR7 | |
| Hydrochloric Acid SCHEMBL4405534 | 0.91 | SOS1 (0.38) | SOS1MAOBMAOAHTR1AHTR7 | |
| SCHEMBL4410352 | 0.91 | KDM4E (0.35) | SOS1MAOBMAOAKDM4EALDH1A1 | |
| SCHEMBL4405632 | 0.91 | MAOB (0.38) | MAOBMAOAHTR2ADRD3DRD2 | |
| SCHEMBL4409300 | 0.90 | MAOB (0.44) | SOS1MAOBMAOADRD3DRD2 | |
| Hydrochloric Acid SCHEMBL4409021 | 0.90 | SOS1 (0.36) | SOS1MAOBMAOAKDM4EALDH1A1 | |
| SCHEMBL4398599 | 0.89 | ALDH1A1 (0.34) | SOS1MAOBMAOAALDH1A1HTR1A | |
| SCHEMBL914187 | 0.88 | RHEB (0.42) | SOS1MAOBMAOAKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL4403798 | 0.88 | MAOB (0.33) | MAOBMAOAHTR1AHTR7HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720859-B1 | CHEMOKINE RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2009-12-23 | — | — | EP | claimed |