Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 2/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 13/20 | 0.40 |
| ▸ | FEN1 | P39748 | 13/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PARG | Q86W56 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1145362 | 0.77 | ALDH1A1 (0.54) | NSD2ALOX5APFEN1KDM4EMEN1 | |
| SCHEMBL31262949 | 0.77 | CA2 (0.59) | KDM4EMEN1MAPTHPGDKMT2A | |
| SCHEMBL9499640 | 0.77 | CA2 (0.59) | KDM4EMEN1MAPTHPGDKMT2A | |
| SCHEMBL13885327 | 0.77 | NSD2 (0.46) | NSD2ALOX5APFEN1KDM4EMEN1 | |
| SCHEMBL2803354 | 0.75 | NSD2 (0.58) | NSD2ALOX5APFEN1KDM4EMEN1 | |
| SCHEMBL20610141 | 0.73 | ALDH1A1 (0.49) | KDM4EMEN1MAPTHPGDKMT2A | |
| SCHEMBL23326924 | 0.71 | NSD2 (0.47) | NSD2ALOX5APFEN1KDM4EMEN1 | |
| SCHEMBL3839029 | 0.71 | KDM4E (0.49) | KDM4EMEN1MAPTHPGDKMT2A | |
| SCHEMBL8831875 | 0.70 | ALOX5AP (0.47) | NSD2ALOX5APFEN1PARG | |
| SCHEMBL22057389 | 0.69 | KDM4E (0.33) | NSD2ALOX5APFEN1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009055674-A1 | PYRROLOPYRIMIDINE ALKYNYL COMPOUNDS AND METHODS OF MAKING AND USING SAME | TARGEGEN INC. (US) | 2009-04-30 | — | — | WO | disclosed |