Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MARS2 | Q96GW9 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 3/20 | 0.52 |
| ▸ | RPLP1 | P05386 | 1/20 | 0.50 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.50 |
| ▸ | RPS17 | P08708 | 1/20 | 0.50 |
| ▸ | RPSA | P08865 | 1/20 | 0.50 |
| ▸ | RPS2 | P15880 | 1/20 | 0.50 |
| ▸ | RPL35A | P18077 | 1/20 | 0.50 |
| ▸ | RPL7 | P18124 | 1/20 | 0.50 |
| ▸ | RPL17 | P18621 | 1/20 | 0.50 |
| ▸ | RPS4Y1 | P22090 | 1/20 | 0.50 |
| ▸ | RPS3 | P23396 | 1/20 | 0.50 |
| ▸ | RPS12 | P25398 | 1/20 | 0.50 |
| ▸ | RPL13 | P26373 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL334444 | 1.00 | ALDH1A1 (0.55) | ALDH1A1CYP3A4LMNASMN1; SMN2MARS2 | |
| SCHEMBL725933 | 1.00 | ALDH1A1 (0.55) | ALDH1A1CYP3A4LMNASMN1; SMN2MARS2 | |
| SCHEMBL251728 | 1.00 | ALDH1A1 (0.55) | ALDH1A1CYP3A4LMNASMN1; SMN2MARS2 | |
| SCHEMBL29167395 | 1.00 | ALDH1A1 (0.55) | ALDH1A1CYP3A4LMNASMN1; SMN2MARS2 | |
| SCHEMBL12172739 | 1.00 | ALDH1A1 (0.55) | ALDH1A1CYP3A4LMNASMN1; SMN2MARS2 | |
| SCHEMBL14183583 | 1.00 | ALDH1A1 (0.55) | ALDH1A1CYP3A4LMNASMN1; SMN2MARS2 | |
| SCHEMBL4247918 | 1.00 | ALDH1A1 (0.55) | ALDH1A1CYP3A4LMNASMN1; SMN2MARS2 | |
| SCHEMBL3912679 | 1.00 | ALDH1A1 (0.55) | ALDH1A1CYP3A4LMNASMN1; SMN2MARS2 | |
| Hydrochloric Acid SCHEMBL11703545 | 0.98 | ALDH1A1 (0.54) | ALDH1A1CYP3A4LMNASMN1; SMN2MARS2 | |
| Hydrochloric Acid SCHEMBL10626955 | 0.98 | ALDH1A1 (0.54) | ALDH1A1CYP3A4LMNASMN1; SMN2MARS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024153952-A1 | COMPOUNDS FOR NUCLEIC ACID CLEAVAGE | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2024-07-25 | — | — | WO | disclosed |
| US-7807838-B2 | Methods for the preparation of HCV polymerase inhibitors | PFIZER INC. (US) | 2010-10-05 | — | — | US | disclosed |
| EP-1430019-B1 | SPHINGOLIPIDS | YISSUM RES DEV CO (IL) | 2009-12-30 | — | — | EP | disclosed |
| US-20090023921-A1 | METHODS FOR THE PREPARATION OF HCV POLYMERASE INHIBITORS | PFIZER INC | 2009-01-22 | — | — | US | disclosed |
| US-7439400-B2 | Amino alcohol ligand and its use in preparation of chiral proparglic tertiary alcohols and tertiary amines via enantioselective addition reaction | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2008-10-21 | — | — | US | disclosed |
| US-6756504-B2 | ENZYME INHIBITORS OF VARIOUS LIPID- RELATED ENZYMES, REDUCING LIPID ACCUMULATION, ANTICANCER AGENTS, ANTIMALARIA AGENTS, ANTIPROTOZOA AGENTS, ANTILIPOLYTIC AGENTS | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2004-06-29 | — | — | US | disclosed |
| US-20030133904-A1 | Sphingolipids | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2003-07-17 | — | — | US | disclosed |
| US-5280027-A | Quinazoline containing compound | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-01-18 | — | — | US | disclosed |
| EP-0459730-A2 | Anti-tumour compounds | ZENECA LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |
| US-4373100-A | ANIMAL FEEDS | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1983-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023921-A1 | METHODS FOR THE PREPARATION OF HCV POLYMERASE INHIBITORS | POLRMT, POLI, POLM | ALDH1A1 789/4885CYP3A4 560/4885LMNA 2037/4885 |
| US-20030133904-A1 | Sphingolipids | SMPD1, SMPD2, SGPL1 | ALDH1A1 817/4885CYP3A4 2892/4885LMNA 613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.