Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 16/20 | 1.00 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.73 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.73 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.66 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.66 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.66 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.66 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.62 |
| ▸ | HTR2A | P28223 | 1/20 | 0.62 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Brotizolam SCHEMBL29396298 | 1.00 | PTAFR (1.00) | PTAFROPRK1PDE4DGABRA1GABRA5 | |
| SCHEMBL11509934 | 0.88 | PTAFR (0.79) | PTAFROPRK1PDE4DGABRA1GABRA5 | |
| SCHEMBL8928433 | 0.88 | PTAFR (0.79) | PTAFROPRK1PDE4DGABRA1GABRA5 | |
| Brotizolam SCHEMBL28319446 | 0.87 | PTAFR (0.76) | PTAFROPRK1PDE4DGABRA1GABRA5 | |
| SCHEMBL9379295 | 0.86 | PTAFR (1.00) | PTAFROPRK1PDE4DGABRA1GABRA5 | |
| Brotizolam SCHEMBL5672939 | 0.85 | PTAFR (0.72) | PTAFROPRK1PDE4DGABRA1GABRA5 | |
| Etizolam SCHEMBL42920 | 0.84 | OPRK1 (1.00) | PTAFROPRK1PDE4D | |
| SCHEMBL8928754 | 0.84 | PTAFR (0.73) | PTAFROPRK1PDE4DGABRA1GABRA5 | |
| SCHEMBL8928388 | 0.84 | PTAFR (0.73) | PTAFROPRK1PDE4DGABRA1GABRA5 | |
| Etizolam SCHEMBL30665015 | 0.84 | OPRK1 (1.00) | PTAFROPRK1PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 7726 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3507371-B1 | COMPOSITIONS FOR TREATING DISEASES AND DISORDERS OF THE NERVOUS SYSTEM | UNIV RUTGERS (US) | 2026-01-28 | — | — | EP | claimed |
| EP-4635514-A2 | METHODS AND COMPOSITIONS FOR TREATING SLEEP APNEA | The Brigham & Women's Hospital, Inc. (US) | 2025-10-22 | — | — | EP | claimed |
| US-20250302814-A1 | METHODS AND COMPOSITIONS FOR TREATING SLEEP APNEA | APNIMED, INC. (DELAWARE) | 2025-10-02 | — | — | US | claimed |
| WO-2025111482-A1 | COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS | BEXSON BIOMEDICAL, INC. (US) | 2025-05-30 | — | — | WO | claimed |
| US-12133922-B2 | Abuse resistant capsule | R.P. SCHERER TECHNOLOGIES, LLC (US) | 2024-11-05 | — | — | US | claimed |
| EP-3863708-B1 | MIXED IONIC CONDUCTORS AND CORRESPONDING DEVICES, SYSTEMS AND METHODS OF MAKING | BATTELLE MEMORIAL INSTITUTE (US) | 2024-09-11 | — | — | EP | claimed |
| EP-4422607-A1 | ORAL AND NASAL COMPOSITIONS AND METHODS OF TREATMENT | Aquestive Therapeutics, Inc. (US) | 2024-09-04 | — | — | EP | claimed |
| CN-118557736-A | Methods and compositions for treating sleep apnea | 布里格姆妇女医院 | 2024-08-30 | — | — | CN | claimed |
| US-20240238250-A1 | METHOD OF USING PIROMELATINE FOR TREATING PARASOMNIAS ASSOCIATED WITH LOSS OF REM SLEEP ATONIA | NEURIM PHARMACEUTICALS (1991) LTD. (IL) | 2024-07-18 | — | — | US | claimed |
| WO-2024150170-A1 | PIROMELATINE FOR TREATING PARASOMNIAS ASSOCIATED WITH LOSS OF REM SLEEP ATONIA | NEURIM PHARMACEUTICALS (1991) LTD. (IL) | 2024-07-18 | — | — | WO | claimed |
| EP-0473612-B1 | FERTILITY ENHANCEMENT | NORTH SYDNEY AREA HEALTH SERV (AU) | 1996-07-31 | — | — | EP | claimed |
| EP-0584285-A1 | IMPROVEMENTS IN BENZODIAZEPINE TREATMENT BY CHOLINESTERASE INHIBITORS | Snorrason, Ernir (IS) | 1994-03-02 | — | — | EP | claimed |
| US-5240922-A | Administering symthetic platelet activating factor antagonist to female mammals to enhance embryo implantation within the uterus | NORTHERN SYDNEY AREA HEALTH SERVICE (AU) | 1993-08-31 | — | — | US | claimed |
| WO-1993013776-A1 | USE OF PAF ANTAGONISTS IN THE TREATMENT OF DYSMENORRHEA | KUTTER EBERHARD (DE) | 1993-07-22 | — | — | WO | claimed |
| WO-1992020328-A2 | IMPROVEMENTS IN BENZODIAZEPINE TREATMENT BY CHOLINESTERASE INHIBITORS | SNORRASON ERNIR (IS) | 1992-11-26 | — | — | WO | claimed |
| EP-0515301-A2 | Improvements in benzodiazepine treatment by cholinesterterase inhibitors | Snorrason, Ernir (IS) | 1992-11-25 | — | — | EP | claimed |
| EP-0473612-A4 | FERTILITY ENHANCEMENT | — | 1992-11-19 | — | — | EP | claimed |
| EP-0473612-A1 | FERTILITY ENHANCEMENT. | NORTH SYDNEY AREA HEALTH SERV (AU) | 1992-03-11 | — | — | EP | claimed |
| WO-1990013299-A1 | FERTILITY ENHANCEMENT | NORTHERN SYDNEY AREA HEALTH SERVICE (AU) | 1990-11-15 | — | — | WO | claimed |
| EP-0384421-A2 | Use of PAF antagonists in the treatment of pathologic changes of the blood gas | BOEHRINGER INGELHEIM KG (DE) | 1990-08-29 | — | — | EP | claimed |