Etizolam

Etizolam

SCHEMBL42920

CCc1cc2c(s1)-n1c(C)nnc1CN=C2c1ccccc1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
OPRK1 P41145 1/20 1.00
PDE4D Q08499 1/20 1.00
PTAFR P25105 19/20 0.74
CYP3A4 P08684 1/20 0.66
ALOX15 P16050 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Etizolam SCHEMBL30665015 1.00 OPRK1 (1.00) OPRK1PDE4DPTAFRCYP3A4ALOX15
Etizolam SCHEMBL10869413 0.95 OPRK1 (0.90) OPRK1PDE4DPTAFRCYP3A4ALOX15
Etizolam SCHEMBL28086661 0.92 OPRK1 (0.85) OPRK1PDE4DPTAFRCYP3A4ALOX15
SCHEMBL8928483 0.92 OPRK1 (0.84) OPRK1PDE4DPTAFRCYP3A4ALOX15
SCHEMBL8928481 0.91 OPRK1 (0.84) OPRK1PDE4DPTAFRCYP3A4ALOX15
SCHEMBL10469718 0.90 PTAFR (0.88) OPRK1PDE4DPTAFRCYP3A4ALOX15
SCHEMBL9667837 0.89 OPRK1 (0.81) OPRK1PDE4DPTAFRCYP3A4ALOX15
SCHEMBL8928449 0.89 OPRK1 (0.80) OPRK1PDE4DPTAFRCYP3A4ALOX15
SCHEMBL8878112 0.89 OPRK1 (0.79) OPRK1PDE4DPTAFRCYP3A4ALOX15
SCHEMBL9673303 0.89 OPRK1 (0.79) OPRK1PDE4DPTAFRCYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3191 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250375421-A1 METHODS OF USING DMT SHULMAN WILLIAM (US) 2025-12-11 US claimed
EP-4656194-A1 COMPOSITION FOR PREVENTING OR TREATING POST-TRAUMATIC STRESS DISORDER, COMPRISING PHOSPHODIESTERASE TYPE 5 INHIBITOR AS ACTIVE INGREDIENT Aribio Co., Ltd (KR) 2025-12-03 EP claimed
US-12396981-B2 Methods of using DMT SHULMAN WILLIAM (US) 2025-08-26 US claimed
EP-4570250-A2 COMBINATIONS COMPRISING BREXPIPRAZOLE OR A SALT THEREOF AND A SECOND DRUG FOR USE IN THE TREATMENT OF A CNS DISORDER Otsuka Pharmaceutical Co., Ltd. (JP) 2025-06-18 EP claimed
US-20250177385-A1 COMBINATIONS COMPRISING BREXPIPRAZOLE OR A SALT THEREOF AND A SECOND DRUG FOR USE IN THE TREATMENT OF A CNS DISORDER OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2025-06-05 US claimed
WO-2025111482-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS AT LOW STOICHIOMETRIC RATIOS BEXSON BIOMEDICAL, INC. (US) 2025-05-30 WO claimed
CN-118703619-A Primer group for detecting SNP locus related to anxiety disorder medication and application thereof 重庆浦济生命科技有限公司 2024-09-27 CN claimed
US-20240299355-A1 METHODS OF USING DMT SHULMAN WILLIAM (US) 2024-09-12 US claimed
WO-2024158189-A1 COMPOSITION FOR PREVENTING OR TREATING POST-TRAUMATIC STRESS DISORDER, COMPRISING PHOSPHODIESTERASE TYPE 5 INHIBITOR AS ACTIVE INGREDIENT 주식회사 아리바이오 2024-08-02 WO claimed
US-20240156811-A1 COMBINATIONS COMPRISING BREXPIPRAZOLE OR A SALT THEREOF AND A SECOND DRUG FOR USE IN THE TREATMENT OF A CNS DISORDER OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2024-05-16 US claimed
EP-0323384-A2 Centrifugal pump BOMBAS ELECTRICAS, S.A. (BOELSA) (ES) 1989-07-05 EP claimed
EP-0322275-A1 Suspension with variable damping AUTOMOBILES PEUGEOT (FR) 1989-06-28 EP claimed
EP-0255814-A2 Process for improving the shelf life of vegetables and fresh fruits Honnay, Raymond (BE) 1988-02-10 EP claimed
EP-0217471-A1 Semiconductor power device for surface mounting PHILIPS COMPOSANTS (FR) 1987-04-08 EP claimed
EP-0086693-B1 SEALING DEVICE FOR A TUNNEL OVEN, WAGON AND TUNNEL OVEN FOR THIS SEALING DEVICE ENTREPRISE HARTMANN PERE & FILS (FR) 1986-06-25 EP claimed
EP-0073989-B1 DEVICE FOR ADJUSTING THE FIT IN SKI BOOTS NORDICA S.p.A (IT) 1986-01-29 EP claimed
EP-0031471-B1 DEVICE FOR MONITORING THE OPERATIONAL CONDITION OF AN ELECTRICAL CONSUMER SIEMENS AKTIENGESELLSCHAFT (DE) 1985-03-06 EP claimed
EP-0052803-B1 HINGE ARM WITH MOUNTING PLATE Arturo Salice S.p.A. (IT) 1984-07-18 EP claimed
EP-0009019-A1 PROCESS AND DEVICE FOR PRODUCING A PACKING, AND THE PACKING PRODUCED. PARISIENNE IMPRESSION (FR) 1980-03-19 EP claimed
WO-1979000409-A1 PROCESS AND DEVICE FOR PRODUCING A PACKING,AND THE PACKING PRODUCED PARISIENNE IMPRESSION CARTONNA (FR) 1979-07-12 WO claimed