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Etizolam

Etizolam

SCHEMBL30665015

CCc1cc2c(s1)-n1c(C)nnc1CN=C2c1ccccc1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ OPRK1 P41145 1/20 1.00
▸ PDE4D Q08499 1/20 1.00
▸ PTAFR P25105 19/20 0.74
▸ CYP3A4 P08684 1/20 0.66
▸ ALOX15 P16050 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Etizolam SCHEMBL42920 1.00 OPRK1 (1.00) OPRK1PDE4DPTAFRCYP3A4ALOX15
Etizolam SCHEMBL10869413 0.95 OPRK1 (0.90) OPRK1PDE4DPTAFRCYP3A4ALOX15
Etizolam SCHEMBL28086661 0.92 OPRK1 (0.85) OPRK1PDE4DPTAFRCYP3A4ALOX15
SCHEMBL8928483 0.92 OPRK1 (0.84) OPRK1PDE4DPTAFRCYP3A4ALOX15
SCHEMBL8928481 0.91 OPRK1 (0.84) OPRK1PDE4DPTAFRCYP3A4ALOX15
SCHEMBL10469718 0.90 PTAFR (0.88) OPRK1PDE4DPTAFRCYP3A4ALOX15
SCHEMBL9667837 0.89 OPRK1 (0.81) OPRK1PDE4DPTAFRCYP3A4ALOX15
SCHEMBL8928449 0.89 OPRK1 (0.80) OPRK1PDE4DPTAFRCYP3A4ALOX15
SCHEMBL8878112 0.89 OPRK1 (0.79) OPRK1PDE4DPTAFRCYP3A4ALOX15
SCHEMBL9673303 0.89 OPRK1 (0.79) OPRK1PDE4DPTAFRCYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116940362-A Use of benzodiazepine to increase sensitivity to oudemansiella radicata following a chronic SSRI regimen 指南针探路者有限公司 2023-10-24 — — CN disclosed