Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5368267 | 0.87 | ALDH1A1 (0.47) | MEN1KMT2AOPRL1POLBALDH1A1 | |
| SCHEMBL4412901 | 0.81 | OPRD1 (0.51) | ALDH1A1NOS2CHRM4CYP4F2CYP4A11 | |
| SCHEMBL301794 | 0.80 | OPRL1 (0.75) | KMT2AOPRL1POLBALDH1A1SIGMAR1 | |
| SCHEMBL795975 | 0.80 | ALDH1A1 (0.56) | MEN1KMT2AOPRL1POLBALDH1A1 | |
| SCHEMBL3441859 | 0.79 | OPRM1 (0.60) | MEN1KMT2AOPRL1ALDH1A1LMNA | |
| SCHEMBL5373048 | 0.79 | OPRM1 (0.60) | MEN1KMT2AOPRL1POLBALDH1A1 | |
| SCHEMBL19280276 | 0.79 | ALDH1A1 (0.46) | OPRL1ALDH1A1PARP10CA12CA1 | |
| SCHEMBL2931056 | 0.79 | OPRM1 (0.52) | MEN1KMT2AOPRL1ALDH1A1LMNA | |
| SCHEMBL2587746 | 0.79 | ALDH1A1 (0.50) | OPRL1ALDH1A1NOS2OPRM1CYP4F2 | |
| SCHEMBL14696653 | 0.79 | PTPN1 (0.48) | MEN1KMT2AOPRL1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1296972-B1 | ARYLMETHYLAMINE DERIVATIVES FOR USE AS TRYPTASE INHIBITORS | AVENTIS PHARMA INC (US) | 2009-12-23 | — | — | EP | disclosed |