SCHEMBL4407230

SCHEMBL4407230

NC1(OC=O)CC1c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 19/20 0.50
MAOA P21397 19/20 0.50
MAOB P27338 19/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9666944 0.76 KDM1A (0.48) KDM1AMAOAMAOB
SCHEMBL12946117 0.71 KDM1A (0.67) KDM1AMAOAMAOB
SCHEMBL6937547 0.69 TRPA1 (0.41) KDM1AMAOAMAOB
SCHEMBL12054818 0.68 KDM1A (0.47) KDM1AMAOAMAOB
SCHEMBL4993041 0.68 SLC18A3 (0.40) KDM1AMAOAMAOB
SCHEMBL23465403 0.67 KDM1A (1.00) KDM1AMAOAMAOB
SCHEMBL15767313 0.67 KDM1A (1.00) KDM1AMAOAMAOB
SCHEMBL4129786 0.67 KDM1A (1.00) KDM1AMAOAMAOB
SCHEMBL15541008 0.67 KDM1A (1.00) KDM1AMAOAMAOB
SCHEMBL15541945 0.67 KDM1A (1.00) KDM1AMAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113372235-B Process for preparing 1-amino-2-phenylcyclopropanecarboxylic acids 佛山奕安赛医药科技有限公司 2022-08-19 CN claimed
CN-113372235-A Process for preparing 1-amino-2-phenylcyclopropanecarboxylic acid 佛山奕安赛医药科技有限公司 2021-09-10 CN claimed
CN-113372235-B Process for preparing 1-amino-2-phenylcyclopropanecarboxylic acids 佛山奕安赛医药科技有限公司 2022-08-19 CN disclosed
CN-113372235-B Process for preparing 1-amino-2-phenylcyclopropanecarboxylic acids 佛山奕安赛医药科技有限公司 2022-08-19 CN disclosed
CN-113372235-A Process for preparing 1-amino-2-phenylcyclopropanecarboxylic acid 佛山奕安赛医药科技有限公司 2021-09-10 CN disclosed
CN-113372235-A Process for preparing 1-amino-2-phenylcyclopropanecarboxylic acid 佛山奕安赛医药科技有限公司 2021-09-10 CN disclosed
US-7589066-B2 Such as N-carbobenzyloxy-phenylalanyl-phenylalanylal; for treating cancer, inflammation, and/or autoimmune diseases; suppresses endogenous antigenic peptide generation THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2009-09-15 US disclosed
EP-1863513-A2 POTENT AND SPECIFIC IMMUNOPROTEASOME INHIBITORS The University of North Carolina at Chapel Hill (US) 2007-12-12 EP disclosed
US-20060241056-A1 Potent and specific immunoproteasome inhibitors UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL 2006-10-26 US disclosed
WO-2006099261-A2 POTENT AND SPECIFIC IMMUNOPROTEASOME INHIBITORS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2006-09-21 WO disclosed
US-4954158-A INHIBIT ETHYLENE PRODUCTION IN PLANTS UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1990-09-04 US disclosed
WO-1990007260-A2 2,3-METHANOPROLINE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1990-07-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060241056-A1 Potent and specific immunoproteasome inhibitors SERPINB1, DNPEP, PSMB2 KDM1A 1761/4885MAOA 3795/4885MAOB 3731/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.