Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | TRPV6 | Q9H1D0 | 2/20 | 0.32 |
| ▸ | MBTD1 | Q05BQ5 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5660853 | 0.80 | — | — | |
| SCHEMBL29117494 | 0.79 | L3MBTL1 (0.36) | CYP2C19L3MBTL1 | |
| SCHEMBL2202748 | 0.77 | — | — | |
| Piperidine SCHEMBL2494101 | 0.71 | HRH4 (0.38) | HRH3 | |
| Biphenyl SCHEMBL27904539 | 0.69 | POLB (0.43) | L3MBTL1 | |
| SCHEMBL165789 | 0.66 | L3MBTL3 (0.48) | CYP2D6CYP2C19L3MBTL3L3MBTL1SLC18A3 | |
| SCHEMBL17619719 | 0.66 | L3MBTL3 (0.48) | CYP2D6CYP2C19L3MBTL3L3MBTL1SLC18A3 | |
| SCHEMBL689798 | 0.65 | HRH4 (0.44) | HRH3SLC18A3 | |
| SCHEMBL14098366 | 0.64 | — | — | |
| SCHEMBL20756261 | 0.64 | L3MBTL3 (0.50) | CYP2D6CYP2C19HRH3L3MBTL3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575960-B1 | 1,4-DIAZABICYCLO 3.2.2 NONANECARBOXAMIDE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI AVENTIS (FR) | 2009-03-18 | — | — | EP | disclosed |