Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 7/20 | 0.34 |
| ▸ | CDK9 | P50750 | 10/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 8/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL988284 | 0.85 | CDK9 (0.41) | KCNN4CDK9CCNT1 | |
| SCHEMBL988283 | 0.85 | CDK9 (0.41) | KCNN4CDK9CCNT1 | |
| SCHEMBL4405216 | 0.83 | CCNT1 (0.38) | KCNN4CDK9CCNT1HTR2CDRD2 | |
| SCHEMBL4412355 | 0.83 | KCNN4 (0.35) | KCNN4CDK9CCNT1HTR2CDRD2 | |
| SCHEMBL985998 | 0.79 | KCNN4 (0.37) | KCNN4CDK9CCNT1 | |
| SCHEMBL13593450 | 0.76 | KCNN4 (0.37) | KCNN4 | |
| SCHEMBL987831 | 0.76 | KCNN4 (0.34) | KCNN4CDK9CCNT1 | |
| SCHEMBL987834 | 0.76 | KCNN4 (0.34) | KCNN4CDK9CCNT1 | |
| SCHEMBL4403806 | 0.76 | GRM1 (0.35) | KCNN4CDK9CCNT1MAP4K4 | |
| SCHEMBL985522 | 0.75 | UCHL1 (0.35) | KCNN4CDK9CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004625-B1 | C-MET PROTEIN KINASE INHIBITORS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | VERTEX PHARMA (US) | 2009-12-30 | — | — | EP | claimed |