Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HIPK2 | Q9H2X6 | 3/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.48 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | ACACA | Q13085 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 2/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2671657 | 0.88 | CSNK2A1 (0.48) | ALDH1A1MAPTHIPK2CSNK2A1ACACB | |
| SCHEMBL30204784 | 0.88 | CSNK2A1 (0.48) | ALDH1A1MAPTHIPK2CSNK2A1ACACB | |
| SCHEMBL4146085 | 0.84 | HIPK2 (0.45) | HIPK2CSNK2A1ACACBACACAPLK1 | |
| SCHEMBL2671662 | 0.80 | CA12 (0.46) | ALDH1A1MAPTHPGDHIPK2CSNK2A1 | |
| SCHEMBL31003157 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MAPTHPGDHIPK2CYP2A6 | |
| SCHEMBL23988833 | 0.78 | ALDH1A1 (0.51) | ALDH1A1MAPTHPGDHIPK2CSNK2A1 | |
| SCHEMBL25270379 | 0.77 | CSNK2A1 (0.53) | ALDH1A1MAPTHIPK2CSNK2A1HCAR3 | |
| SCHEMBL2671305 | 0.75 | PLAU (0.55) | ALDH1A1MAPTHIPK2CSNK2A1ACACB | |
| SCHEMBL8297790 | 0.75 | WNT3A (0.41) | ALDH1A1HPGDCYP2A6MEN1KMT2A | |
| SCHEMBL8275614 | 0.74 | LCK (0.50) | ALDH1A1CSNK2A1L3MBTL1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012056372-A1 | N1/N2-LACTAM ACETYL-CoA CARBOXYLASE INHIBITORS | PFIZER INC. (US) | 2012-05-03 | — | — | WO | disclosed |