Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.50 |
| ▸ | C1S | P09871 | 1/20 | 0.50 |
| ▸ | F12 | P00748 | 4/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.46 |
| ▸ | HIPK2 | Q9H2X6 | 2/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | NCF1 | P14598 | 1/20 | 0.46 |
| ▸ | NOS3 | P29474 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.46 |
| ▸ | PLG | P00747 | 2/20 | 0.46 |
| ▸ | F11 | P03951 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL393250 | 0.85 | GABRP (0.53) | ALDH1A1MAPTROCK1C1SF12 | |
| SCHEMBL5735418 | 0.85 | CSNK2A1 (0.61) | ROCK1C1SF12CSNK2A1HIPK2 | |
| Hydrochloric Acid SCHEMBL6439046 | 0.83 | GABRP (0.51) | ALDH1A1MAPTROCK1C1SF12 | |
| Hydrochloric Acid SCHEMBL16246816 | 0.83 | CSNK2A1 (0.59) | ROCK1C1SF12CSNK2A1HIPK2 | |
| SCHEMBL30159603 | 0.83 | LCK (0.54) | ALDH1A1MAPTHPGDROCK1C1S | |
| SCHEMBL18640167 | 0.83 | LCK (0.54) | ALDH1A1MAPTHPGDROCK1C1S | |
| SCHEMBL22000160 | 0.83 | PLK1 (0.52) | ROCK1C1SCSNK2A1HIPK2PLAU | |
| SCHEMBL31003157 | 0.81 | ALDH1A1 (0.53) | ALDH1A1MAPTHPGDC1SHIPK2 | |
| SCHEMBL7902184 | 0.80 | F7 (0.57) | ALDH1A1MAPTROCK1F11MAP4K4 | |
| SCHEMBL27512136 | 0.79 | LMNA (0.50) | ALDH1A1MAPTROCK1C1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210340105-A1 | AMINOPYRIDINE COMPOUNDS AND METHODS FOR THE PREPARATION AND USE THEREOF | Cortexyme, Inc. (US) | 2021-11-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210340105-A1 | AMINOPYRIDINE COMPOUNDS AND METHODS FOR THE PREPARATION AND USE THEREOF | ENPEP, DNPEP, ANPEP | ALDH1A1 2722/4885MAPT 973/4885HPGD 441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.