Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.68 |
| ▸ | HTT | P42858 | 5/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.68 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.68 |
| ▸ | CCR6 | P51684 | 1/20 | 0.68 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12775381 | 0.83 | ALDH1A1 (0.72) | ALDH1A1HTTHPGDMAPTCACNA1B | |
| SCHEMBL10977161 | 0.82 | ALDH1A1 (0.70) | ALDH1A1HTTHPGDMAPTCACNA1B | |
| SCHEMBL22792082 | 0.81 | ALDH1A1 (0.51) | ALDH1A1HTTHPGDMAPTCACNA1B | |
| SCHEMBL4405847 | 0.81 | ALDH1A1 (0.64) | ALDH1A1HTTHPGDMAPTCACNA1B | |
| SCHEMBL2006114 | 0.81 | ALDH1A1 (1.00) | ALDH1A1HTTHPGDMAPTCACNA1B | |
| SCHEMBL4407371 | 0.81 | ALDH1A1 (0.79) | ALDH1A1HTTHPGDMAPTCACNA1B | |
| SCHEMBL4408113 | 0.81 | ALDH1A1 (0.68) | ALDH1A1HTTHPGDMAPTCACNA1B | |
| SCHEMBL22952393 | 0.80 | ALDH1A1 (0.57) | ALDH1A1HTTHPGDMAPTCACNA1B | |
| SCHEMBL25669625 | 0.80 | MAPK10 (0.54) | ALDH1A1HTTHPGDMAPTCACNA1B | |
| SCHEMBL25669620 | 0.79 | ALDH1A1 (0.53) | ALDH1A1HTTHPGDMAPTCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12024500-B2 | Five-membered ring-substituted pyridazinol compounds and derivatives, preparation methods, herbicidal compositions and applications thereof | QINGDAO KINGAGROOT CHEMICAL COMPOUND CO., LTD. (CN) | 2024-07-02 | — | — | US | disclosed |
| CN-104086485-B | Prepare the method for poly-substituted quinoline type aromatic ring pyridine derivate | TSINGHUA UNIVERSITY (CN) | 2016-03-30 | — | — | CN | disclosed |
| CN-104086485-A | Method for preparing multi-substituted quinoline-type aromatic ring pyridine derivatives | UNIV TSINGHUA | 2014-10-08 | — | — | CN | disclosed |
| US-7902373-B2 | asthma; for treating prostaglandin D2 mediated diseases; e.g. 6-(3-fluorophenyl)-N-[1-(1-methyl-1H-tetrazol-5-yl)piperidin-4-yl]nicotinamide | PFIZER INC (US) | 2011-03-08 | — | — | US | disclosed |
| EP-1859782-B1 | Composition for coloring and/or lightening human hair comprising tetrazoles | HENKEL AG & CO KGAA (DE) | 2009-12-30 | — | — | EP | disclosed |
| US-20080146569-A1 | Nicotinamide Derivatives | PFIZER INC. | 2008-06-19 | — | — | US | disclosed |
| EP-1859782-A1 | Composition for coloring and/or lightening human hair comprising tetrazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |
| EP-0994881-B1 | ORTHO-METALATION PROCESS FOR THE SYNTHESIS OF 2-SUBSTITUTED-1-(TETRAZOL-5-YL)BENZENES | ZAMBON SPA (IT) | 2002-09-18 | — | — | EP | disclosed |
| US-6271375-B1 | ESPECIALLY PREPARATION OF TASOSARTAN; GRIGNARD REAGENTS | ZAMBON GROUP S.P.A. (IT) | 2001-08-07 | — | — | US | disclosed |
| CN-1274383-A | Triptycene derivatives and their use in optoelectronic devices, in particular as electroluminescent materials | AXIVA GMBH (DE) | 2000-11-22 | — | — | CN | disclosed |
| EP-0994881-A1 | ORTHO-METALATION PROCESS FOR THE SYNTHESIS OF 2-SUBSTITUTED-1-(TETRAZOL-5-YL)BENZENES | ZAMBON GROUP S.p.A. (IT) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999001459-A1 | ORTHO-METALATION PROCESS FOR THE SYNTHESIS OF 2-SUBSTITUTED-1-(TETRAZOL-5-YL)BENZENES | ZAMBON GROUP S.P.A. (IT) | 1999-01-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12024500-B2 | Five-membered ring-substituted pyridazinol compounds and derivatives, preparation methods, herbicidal compositions and applications thereof | DDT, CYP3A5, CYP4B1 | ALDH1A1 383/4885HTT 2307/4885HPGD 864/4885 |
| US-20080146569-A1 | Nicotinamide Derivatives | NNT, NAMPT, NADK | ALDH1A1 148/4885HTT 3053/4885HPGD 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.