Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 15/20 | 0.68 |
| ▸ | MAPT | P10636 | 5/20 | 0.68 |
| ▸ | HTT | P42858 | 4/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.68 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.68 |
| ▸ | CCR6 | P51684 | 1/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4405847 | 0.85 | ALDH1A1 (0.64) | ALDH1A1MAPTHTTHPGDCACNA1B | |
| SCHEMBL10977161 | 0.82 | ALDH1A1 (0.70) | ALDH1A1MAPTHTTHPGDCACNA1B | |
| SCHEMBL5551503 | 0.81 | ALDH1A1 (0.70) | ALDH1A1MAPTHTTHPGDCACNA1B | |
| SCHEMBL6100503 | 0.81 | ALDH1A1 (0.47) | ALDH1A1MAPTHTTHPGDCACNA1B | |
| SCHEMBL5549540 | 0.81 | L3MBTL1 (0.52) | ALDH1A1MAPTHTTHPGDCACNA1B | |
| SCHEMBL310917 | 0.81 | ALDH1A1 (0.47) | ALDH1A1MAPTHTTHPGDCACNA1B | |
| SCHEMBL8464852 | 0.81 | ALDH1A1 (0.49) | ALDH1A1MAPTHTTHPGDCACNA1B | |
| SCHEMBL4407904 | 0.81 | ALDH1A1 (0.68) | ALDH1A1MAPTHTTHPGDCACNA1B | |
| SCHEMBL2006114 | 0.81 | ALDH1A1 (1.00) | ALDH1A1MAPTHTTHPGDCACNA1B | |
| SCHEMBL4407371 | 0.81 | ALDH1A1 (0.79) | ALDH1A1MAPTHTTHPGDCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101270097-B | Process for production of 1-aryl-5-(trifluoromethyl)-1H-tetrazoles | TOYO BOSEKI | 2011-04-13 | — | — | CN | disclosed |
| EP-1859782-B1 | Composition for coloring and/or lightening human hair comprising tetrazoles | HENKEL AG & CO KGAA (DE) | 2009-12-30 | — | — | EP | disclosed |
| CN-100424069-C | Preparation method of N-aryl-2, 2, 2-trifluoro acetimidoyl chloride | TOYO KASEI KOGYO CO LTD (JP) | 2008-10-08 | — | — | CN | disclosed |
| CN-101270097-A | Process for production of 1-aryl-5-(trifluoromethyl)-1H-tetrazoles | TOYO KASEI KOGYO CO LTD (JP) | 2008-09-24 | — | — | CN | disclosed |
| EP-1859782-A1 | Composition for coloring and/or lightening human hair comprising tetrazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |
| US-7282609-B2 | Process for production of 1-aryl-5-(trifluoromethyl)-1H-tetrazoles | TOYO KASEI KOGYO COMPANY LIMITED (JP) | 2007-10-16 | — | — | US | disclosed |
| US-7282609-B2 | Process for production of 1-aryl-5-(trifluoromethyl)-1H-tetrazoles | TOYO KASEI KOGYO COMPANY LIMITED (JP) | 2007-10-16 | — | — | US | disclosed |
| US-7282609-B2 | Process for production of 1-aryl-5-(trifluoromethyl)-1H-tetrazoles | TOYO KASEI KOGYO COMPANY LIMITED (JP) | 2007-10-16 | — | — | US | disclosed |
| US-20070106080-A1 | Process for production of 1-aryl-5-(trifluoromethyl)-1h-tetrazoles | TOYO KASEI KOGYO COMPANY LIMITED (JP) | 2007-05-10 | — | — | US | disclosed |
| US-20070106080-A1 | Process for production of 1-aryl-5-(trifluoromethyl)-1h-tetrazoles | TOYO KASEI KOGYO COMPANY LIMITED (JP) | 2007-05-10 | — | — | US | disclosed |
| US-20070106080-A1 | Process for production of 1-aryl-5-(trifluoromethyl)-1h-tetrazoles | TOYO KASEI KOGYO COMPANY LIMITED (JP) | 2007-05-10 | — | — | US | disclosed |
| CN-1863765-A | Preparation method of 1-aryl-5- (trifluoromethyl) -1H-tetrazole | TOYO KASEI KOGYO CO LTD (JP) | 2006-11-15 | — | — | CN | disclosed |
| EP-1671945-A1 | PROCESS FOR PRODUCTION OF 1-ARYL-5-(TRIFLUOROMETHYL)-1H- TETRAZOLES | Toyo Kasei Kogyo Company Limited (JP) | 2006-06-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070106080-A1 | Process for production of 1-aryl-5-(trifluoromethyl)-1h-tetrazoles | TH, NAT1, PAH | ALDH1A1 608/4885MAPT 3643/4885HTT 1399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.