Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.35 |
| ▸ | CA2 | P00918 | 6/20 | 0.35 |
| ▸ | CA12 | O43570 | 5/20 | 0.35 |
| ▸ | CA9 | Q16790 | 5/20 | 0.35 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PPM1B | O75688 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14289918 | 1.00 | CA1 (0.35) | CA1CA2CA12CA9CAPN9 | |
| SCHEMBL7664394 | 0.85 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL7642397 | 0.79 | CHRNB2 (0.37) | CYP1A2 | |
| SCHEMBL12271258 | 0.79 | CA1 (0.35) | CA1CA2CA12CA9CAPN9 | |
| SCHEMBL20073039 | 0.78 | ALDH1A1 (0.46) | CA1CA2CA12CA9CAPN9 | |
| SCHEMBL21905196 | 0.78 | ALDH1A1 (0.46) | CA1CA2CA12CA9CAPN9 | |
| SCHEMBL20063850 | 0.78 | ALDH1A1 (0.46) | CA1CA2CA12CA9CAPN9 | |
| SCHEMBL14289917 | 0.76 | PPM1B (0.38) | CA1CA2CA12CA9CAPN9 | |
| SCHEMBL8914013 | 0.76 | ALDH1A1 (0.48) | CA1CA2CA12CA9CAPN9 | |
| SCHEMBL2705851 | 0.76 | ALDH1A1 (0.48) | CA1CA2CA12CA9CAPN9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2543340-A1 | Novel hydrophilic polymers as medical lubricants and gels | TRUSTEES OF BOSTON UNIVERSITY (US) | 2013-01-09 | — | — | EP | disclosed |
| US-20090208589-A1 | NOVEL HYDROPHILIC POLYMERS AS MEDICAL LUBRICANTS AND GELS | TRUSTEES OF BOSTON UNIVERSITY (US) | 2009-08-20 | — | — | US | disclosed |
| EP-2019647-A2 | NOVEL HYDROPHILIC POLYMERS AS MEDICAL LUBRICANTS AND GELS | TRUSTEES OF BOSTON UNIVERSITY (US) | 2009-02-04 | — | — | EP | disclosed |
| WO-2007136738-A2 | NOVEL HYDROPHILIC POLYMERS AS MEDICAL LUBRICANTS AND GELS | TRUSTEES OF BOSTON UNIVERSITY (US) | 2007-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090208589-A1 | NOVEL HYDROPHILIC POLYMERS AS MEDICAL LUBRICANTS AND GELS | CD44, AQP3, VCL | CA1 1556/4885CA2 4583/4885CA12 1057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.