SCHEMBL4408787

SCHEMBL4408787

CCCC1(C)Cc2c(F)cccc2C(c2cnc3ccccc3c2)=N1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 2/20 0.37
AKR1C2 P52895 2/20 0.37
RORC P51449 1/20 0.36
NR2F2 P24468 1/20 0.36
PARP10 Q53GL7 1/20 0.36
PARP11 Q9NR21 1/20 0.36
BRD4 O60885 2/20 0.36
CREBBP Q92793 2/20 0.36
NISCH Q9Y2I1 1/20 0.35
FASN P49327 2/20 0.35
TRPV3 Q8NET8 1/20 0.35
BIRC5 O15392 1/20 0.34
PDGFRB P09619 2/20 0.34
PDGFRA P16234 2/20 0.34
MAP4K4 O95819 1/20 0.34
CSNK1G2 P78368 1/20 0.34
CLK4 Q9HAZ1 1/20 0.34
MKNK2 Q9HBH9 1/20 0.34
MAP4K5 Q9Y4K4 1/20 0.34
HSP90AA1 P07900 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29919637 1.00 AKR1C3 (0.37) AKR1C3AKR1C2RORCNR2F2PARP10
SCHEMBL4520502 0.92 AKR1C3 (0.41) AKR1C3AKR1C2RORCNR2F2PARP10
SCHEMBL29919676 0.92 AKR1C3 (0.41) AKR1C3AKR1C2RORCNR2F2PARP10
SCHEMBL13506385 0.87 AKR1C3 (0.37) AKR1C3AKR1C2RORCNR2F2PARP10
SCHEMBL4405493 0.85 AKR1C3 (0.43) AKR1C3AKR1C2RORCNR2F2PARP10
SCHEMBL29678248 0.85 AKR1C3 (0.43) AKR1C3AKR1C2RORCNR2F2PARP10
SCHEMBL4511543 0.84 NR2F2 (0.39) NR2F2PARP10PARP11BRD4CREBBP
Hydrochloric Acid SCHEMBL4510693 0.84 AKR1C3 (0.43) AKR1C3AKR1C2RORCNR2F2PARP10
Sulfuric Acid SCHEMBL4522657 0.80 AKR1C3 (0.44) AKR1C3AKR1C2RORCNR2F2PARP10
Oxalic Acid SCHEMBL4521269 0.80 AKR1C3 (0.48) AKR1C3AKR1C2RORCNR2F2PARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230111656-A1 METHODS OF CONTROLLING OR PREVENTING INFESTATION OF SOYBEAN PLANTS BY THE PHYTOPATHOGENIC MICROORGANISM CORYNESPORA CASSIICOLA SYNGENTA CROP PROTECTION AG (CH) 2023-04-13 US claimed
EP-4117436-A1 METHODS OF CONTROLLING OR PREVENTING INFESTATION OF PLANTS BY THE PHYTOPATHOGENIC MICROORGANISM CORYNESPORA CASSIICOLA Syngenta Crop Protection AG (CH) 2023-01-18 EP claimed
WO-2021180974-A1 METHODS OF CONTROLLING OR PREVENTING INFESTATION OF PLANTS BY THE PHYTOPATHOGENIC MICROORGANISM CORYNESPORA CASSIICOLA SYNGENTA CROP PROTECTION AG (CH) 2021-09-16 WO claimed
US-20170094971-A1 PLANT DISEASE CONTROL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASE BY APPLICATION OF SAME MITSUI CHEMICALS AGRO, INC. (JP) 2017-04-06 US claimed
EP-3150069-A1 PLANT DISEASE CONTROL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASE BY APPLYING THE SAME Mitsui Chemicals Agro, Inc. (JP) 2017-04-05 EP claimed
EP-1736471-B1 3-(DIHYDRO(TETRAHYDRO)ISOQUINOLIN-1-YL)QUINOLINES MITSUI CHEMICALS AGRO INC (JP) 2014-01-08 EP claimed
EP-2103214-B1 USE OF QUINOLINE COMPOUNDS OR SALTS THEREOF AS ACTIVE INGREDIENTS IN SOIL- OR SEED-TREATING AGENTS AND METHOD FOR CONTROL OF PLANT DISEASE MITSUI CHEMICALS AGRO INC (JP) 2013-10-23 EP claimed
US-20120282349-A1 PLANT DISEASE CONTROL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASE BY APPLYING THE SAME MITSUI CHEMICALS AGRO, INC. (JP) 2012-11-08 US claimed
EP-2517562-A1 PLANT DISEASE CONTROL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES BY APPLYING THE COMPOSITION Mitsui Chemicals Agro, Inc. (JP) 2012-10-31 EP claimed
US-20090325998-A1 SOIL TREATING AGENT OR SEED TREATING AGENT COMPRISING QUINOLINE COMPOUNDS OR SALTS THEREOF AS ACTIVE INGREDIENT,OR METHOD FOR PREVENTING PLANT DISEASES BY USING THE SAME MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) 2009-12-31 US claimed
US-7632783-B2 fungicides, pesticides for protecting rice crop, tomatoes, cucumbers and green beans; 3-(5-fluoro-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)quinoline MITSUI CHEMICALS AGRO, INC. (JP) 2009-12-15 US claimed
EP-2103214-A1 SOIL- OR SEED-TREATING AGENT COMPRISING QUINOLINE COMPOUND OR SALT THEREOF AS ACTIVE INGREDIENT, OR METHOD FOR CONTROL OF PLANT DISEASE USING THE SAME Sankyo Agro Company, Limited (JP) 2009-09-23 EP claimed
US-20080275242-A1 3-(Dihydro(Tetrahydro)Isoquinolin-1-Yl)Quinoline Compound MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) 2008-11-06 US claimed
EP-1736471-A1 3-(DIHYDRO(TETRAHYDRO)ISOQUINOLIN-1-YL)QUINOLINES Sankyo Agro Company, Limited (JP) 2006-12-27 EP claimed
US-12310365-B2 Plant disease control composition and method for controlling plant disease by applying the same MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) 2025-05-27 US disclosed
US-20240065267-A1 PLANT DISEASE CONTROL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASE BY APPLYING THE SAME MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) 2024-02-29 US disclosed
US-11805779-B2 Plant disease control composition and method for controlling plant disease by applying the same MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) 2023-11-07 US disclosed
EP-2103214-A1 SOIL- OR SEED-TREATING AGENT COMPRISING QUINOLINE COMPOUND OR SALT THEREOF AS ACTIVE INGREDIENT, OR METHOD FOR CONTROL OF PLANT DISEASE USING THE SAME Sankyo Agro Company, Limited (JP) 2009-09-23 EP disclosed
US-20080275242-A1 3-(Dihydro(Tetrahydro)Isoquinolin-1-Yl)Quinoline Compound MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) 2008-11-06 US disclosed
EP-1736471-A1 3-(DIHYDRO(TETRAHYDRO)ISOQUINOLIN-1-YL)QUINOLINES Sankyo Agro Company, Limited (JP) 2006-12-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170094971-A1 PLANT DISEASE CONTROL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASE BY APPLICATION OF SAME BROX, HAX1, CHRM1 AKR1C3 1908/4885AKR1C2 2240/4885RORC 2440/4885
US-20240065267-A1 PLANT DISEASE CONTROL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASE BY APPLYING THE SAME SNX1, HAX1, BROX AKR1C3 3534/4885AKR1C2 3722/4885RORC 3136/4885
US-12310365-B2 Plant disease control composition and method for controlling plant disease by applying the same SNX1, HAX1, BROX AKR1C3 3534/4885AKR1C2 3722/4885RORC 3136/4885
US-20080275242-A1 3-(Dihydro(Tetrahydro)Isoquinolin-1-Yl)Quinoline Compound QTRT1, RABL3, RECQL AKR1C3 1232/4885AKR1C2 1859/4885RORC 1500/4885
US-20120282349-A1 PLANT DISEASE CONTROL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASE BY APPLYING THE SAME SNX1, BROX, HAX1 AKR1C3 3017/4885AKR1C2 3357/4885RORC 2941/4885
US-11805779-B2 Plant disease control composition and method for controlling plant disease by applying the same SNX1, HAX1, BROX AKR1C3 3534/4885AKR1C2 3722/4885RORC 3136/4885
US-20090325998-A1 SOIL TREATING AGENT OR SEED TREATING AGENT COMPRISING QUINOLINE COMPOUNDS OR SALTS THEREOF AS ACTIVE INGREDIENT,OR METHOD FOR PREVENTING PLANT DISEASES BY USING THE SAME RABL3, H1-3, RECQL AKR1C3 454/4885AKR1C2 1160/4885RORC 2745/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.