Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4397434 | 0.87 | RAB9A (0.57) | RAB9AL3MBTL1NPC1SMN1; SMN2CYP19A1 | |
| SCHEMBL4409236 | 0.81 | RAB9A (0.59) | RAB9AL3MBTL1NPC1SMN1; SMN2CYP19A1 | |
| SCHEMBL4407425 | 0.80 | RAB9A (0.57) | RAB9AL3MBTL1NPC1SMN1; SMN2CYP19A1 | |
| SCHEMBL4410891 | 0.79 | RAB9A (0.56) | RAB9AL3MBTL1NPC1SMN1; SMN2CYP19A1 | |
| SCHEMBL4414649 | 0.75 | RAB9A (0.65) | RAB9AL3MBTL1NPC1SMN1; SMN2CYP19A1 | |
| SCHEMBL3295862 | 0.74 | RAB9A (0.50) | RAB9AL3MBTL1NPC1SMN1; SMN2CYP19A1 | |
| SCHEMBL3294669 | 0.74 | RAB9A (0.50) | RAB9AL3MBTL1NPC1SMN1; SMN2HDAC6 | |
| SCHEMBL4406039 | 0.72 | LMNA (0.37) | RAB9AL3MBTL1NPC1SMN1; SMN2LMNA | |
| SCHEMBL4413954 | 0.72 | RAB9A (0.65) | RAB9AL3MBTL1NPC1SMN1; SMN2CYP19A1 | |
| SCHEMBL4406033 | 0.71 | ABCG2 (0.44) | RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1859782-B1 | Composition for coloring and/or lightening human hair comprising tetrazoles | HENKEL AG & CO KGAA (DE) | 2009-12-30 | — | — | EP | disclosed |
| EP-1859782-A1 | Composition for coloring and/or lightening human hair comprising tetrazoles | Henkel Kommanditgesellschaft auf Aktien (DE) | 2007-11-28 | — | — | EP | disclosed |