Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2699840 | 0.86 | ALDH1A1 (0.47) | ALDH1A1TSHRHTTTDP1TP53 | |
| SCHEMBL5512527 | 0.86 | ALDH1A1 (0.48) | ALDH1A1TSHRGLATDP1TP53 | |
| SCHEMBL5515003 | 0.79 | TP53 (0.49) | ALDH1A1TSHRHTTTDP1TP53 | |
| Hydrazine SCHEMBL27419993 | 0.79 | TP53 (0.50) | ALDH1A1TSHRGLAHTTTDP1 | |
| SCHEMBL1668024 | 0.78 | TP53 (0.53) | ALDH1A1TSHRGLAHTTTDP1 | |
| Propylamine SCHEMBL28083663 | 0.78 | TP53 (0.47) | ALDH1A1TSHRHTTTDP1TP53 | |
| SCHEMBL4286533 | 0.78 | ESR1 (0.48) | ALDH1A1TSHRHTTKMT2AKDM4E | |
| SCHEMBL10869825 | 0.77 | ALDH1A1 (0.45) | ALDH1A1TSHRHTTTP53PTPN1 | |
| SCHEMBL4294748 | 0.77 | TSHR (0.43) | ALDH1A1TSHRGLATDP1TP53 | |
| SCHEMBL5510917 | 0.77 | LTB4R2 (0.47) | ALDH1A1TSHRTP53ALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015008-B1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECH INC (US) | 2015-08-05 | — | — | EP | disclosed |
| US-20090324540-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2009-12-31 | — | — | US | disclosed |
| US-7553872-B2 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC. (US) | 2009-06-30 | — | — | US | disclosed |
| EP-0993831-B1 | Compounds and compositions for delivering active agents | EMISPHERE TECH INC (US) | 2008-01-09 | — | — | EP | disclosed |
| US-7125910-B2 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC. (US) | 2006-10-24 | — | — | US | disclosed |
| EP-1015008-A4 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECH INC (US) | 2006-08-09 | — | — | EP | disclosed |
| US-20060166859-A1 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC. (US) | 2006-07-27 | — | — | US | disclosed |
| US-7071214-B2 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC. (US) | 2006-07-04 | — | — | US | disclosed |
| EP-1093819-B1 | Compound and composition for delivering active agents | EMISPHERE TECH INC (US) | 2006-05-03 | — | — | EP | disclosed |
| US-20040022856-A1 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC. | 2004-02-05 | — | — | US | disclosed |
| US-6051561-A | MIXTURE OF ACTIVE MATERIAL AND A CARBOXYLATED PHENOL COMPOUND | EMISPHERE TECHNOLOGIES INC. (US) | 2000-04-18 | — | — | US | disclosed |
| US-5990166-A | O-(1-CARBOXYOCTYLCARBONYLAMINO)PHENOL AS A CARRIER; DRUG DELIVERY; ACID RESISTANCE; FORMING NONCOVALENT MIXTURES WITH BIOLOGICALLY ACTIVE AGENTS FOR ORAL ADMINISTRATION; E.G., CALCITONIN, INSULIN, POLYSACCHARIDES, MUCOPOLYSACCHARIDES | EMISPHERE TECHNOLOGIES, INC. (US) | 1999-11-23 | — | — | US | disclosed |
| WO-1998034632-A9 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECH INC (US) | 1999-09-02 | — | — | WO | disclosed |
| US-5939381-A | 4-(4-(PHENOXYACETYL)AMINOPHENYL)BUTYRIC ACID AS A CARRIER FOR DRUG DELIVERY | EMISPHERE TECHNOLOGIES, INC. (US) | 1999-08-17 | — | — | US | disclosed |
| US-5879681-A | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLGIES INC. (US) | 1999-03-09 | — | — | US | disclosed |
| US-5876710-A | DRUG DELIVERY; USING A BROMINATED BENZAMIDE COMPOUND | EMISPHERE TECHNOLOGIES INC. (US) | 1999-03-02 | — | — | US | disclosed |
| US-5804688-A | 6-N-(3,5-DICHLORO-2-HYDROXYBENZOYL)AMINOCAPROIC ACID | EMISPHERE TECHNOLOGIES, INC. (US) | 1998-09-08 | — | — | US | disclosed |
| WO-1998034632-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 1998-08-13 | — | — | WO | disclosed |
| US-5776888-A | 3-(DIMETHOXYBENZOYLAMINOPHENYL) PROPIONIC ACID | EMISPHERE TECHNOLOGIES, INC. (US) | 1998-07-07 | — | — | US | disclosed |
| US-5773647-A | USING A AROMATIC COMPOUND CONTAINING AMIDE AND CARBOXY GROUPS | EMISPHERE TECHNOLOGIES, INC. (US) | 1998-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040022856-A1 | Compounds and compositions for delivering active agents | ABCB4, ABCB7, ALPP | ALDH1A1 1939/4885TSHR 3659/4885GLA 510/4885 |
| US-20060166859-A1 | Compounds and compositions for delivering active agents | ABCB4, ABCB7, ALPP | ALDH1A1 1939/4885TSHR 3659/4885GLA 510/4885 |
| US-20090324540-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | ABCB4, ABCB7, ALPP | ALDH1A1 1939/4885TSHR 3659/4885GLA 510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.