SCHEMBL381601

SCHEMBL381601

Clc1ccccc1-c1cccc(Cl)c1Cl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.52
DPP4 P27487 1/20 0.48
TSHR P16473 2/20 0.47
LMNA P02545 2/20 0.47
NOTUM Q6P988 1/20 0.45
IDO1 P14902 1/20 0.45
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
TP53 P04637 1/20 0.44
HPGD P15428 1/20 0.44
NUDT1 P36639 2/20 0.44
PTPRC P08575 1/20 0.43
P2RX7 Q99572 1/20 0.43
TAAR1 Q96RJ0 1/20 0.43
CYP2D6 P10635 1/20 0.42
MAOA P21397 1/20 0.42
MAPK1 P28482 1/20 0.42
ADRA1A P35348 1/20 0.42
SCN4A P35499 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29385608 1.00 CYP2A6 (0.52) CYP2A6DPP4TSHRLMNANOTUM
SCHEMBL440943 0.91 TSHR (0.52) CYP2A6TSHRLMNANOTUMIDO1
Biphenyl SCHEMBL10457113 0.91 CYP2A6 (0.62) CYP2A6DPP4LMNANOTUMIDO1
SCHEMBL29802156 0.85 CYP2A6 (0.67) CYP2A6DPP4TSHRLMNANOTUM
SCHEMBL671133 0.85 CYP2A6 (0.67) CYP2A6DPP4TSHRLMNANOTUM
SCHEMBL29883244 0.85 CYP2A6 (0.67) CYP2A6DPP4TSHRLMNANOTUM
SCHEMBL2935720 0.84 AHR (0.48) CYP2A6DPP4TSHRLMNANOTUM
Ammonia Solution, Strong SCHEMBL735046 0.82 CYP2A6 (0.63) CYP2A6DPP4TSHRLMNANOTUM
Hydrogen Sulfide SCHEMBL8574751 0.82 CYP2A6 (0.63) CYP2A6DPP4TSHRLMNANOTUM
Hydrogen Sulfide SCHEMBL9195473 0.82 CYP2A6 (0.63) CYP2A6DPP4TSHRLMNANOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 483 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119361834-A Electrolyte and battery and electricity utilization device containing same 浙江大学 2025-01-24 CN claimed
CN-118639436-A Evaporation-driven power generation fabric and preparation method thereof 武汉纺织大学 2024-09-13 CN claimed
CN-218274022-U Soft shielding type automotive wiring harness 徐州市银铃新能源科技有限公司 2023-01-10 CN claimed
CN-111665313-B Method for determining polychlorinated biphenyl compounds in aquatic products 孟祥龙 2022-10-11 CN claimed
CN-217010624-U Liquid-cooled motor and vehicle 江苏爱玛车业科技有限公司 2022-07-19 CN claimed
CN-114196618-A Exposure system of organic flame retardant to human respiratory tract cells and preparation method and application thereof 广东工业大学 2022-03-18 CN claimed
CN-109762776-B Microbial agent for improving soil quality, preparation method and application 中国环境科学研究院 2022-02-01 CN claimed
CN-109868243-B Microbial agent for accelerating soil organic matter pollution remediation, preparation method and application thereof 中国环境科学研究院 2022-02-01 CN claimed
CN-113945650-A Method for simultaneously analyzing persistent organic pollutants in grains 国家粮食和物资储备局科学研究院 2022-01-18 CN claimed
CN-113773998-A PCBs composite degrading microbial inoculum and application thereof 广东海洋大学 2021-12-10 CN claimed
WO-2018148224-A1 PHOSPHOLIPID ETHER (PLE) CAR T CELL TUMOR TARGETING (CTCT) AGENTS Seattle Children's Hospital (dba Seattle Children's Research Institute) (US) 2018-08-16 WO claimed
EP-1837032-A2 MAGNETORESONANCE PREPARATIONS, DEVICE FOR INDIVIDUALLY SELECTING SAID PREPARATIONS FOR INCREASING AN ORGANISM LIFE ACTIVITY IN ACTUAL ENVIRONMENTAL CONDITIONS Gotovsky, Mikhail Yurievich (RU) 2007-09-26 EP claimed
US-20060281961-A1 Functional transition metal silicates KANUMURU RAHUL RAJU (IN) 2006-12-14 US claimed
US-6380454-B1 DISTILLATION; SUPPLYING SODIUM; DECHLORINATION BY SALT FORMATION CANADIAN IMPERIAL BANK OF COMMERCE (CA) 2002-04-30 US claimed
EP-0503831-B1 Destruction of polychlorinated biphenyls ONTARIO HYDRO (CA) 1997-09-17 EP claimed
EP-0503831-A1 Destruction of polychlorinated biphenyls ONTARIO HYDRO (CA) 1992-09-16 EP claimed
US-4490266-A Process for the preparation of liquids of low inflammability and high viscosity index and the use thereof BAYER AKTIENGESELLSCHAFT (DE) 1984-12-25 US claimed
US-4357213-A Method of recovery of liquid chlorine derivatives of hydrocarbons MANTULO ALEXANDR P 1982-11-02 US claimed
US-4236973-A BY PASSING A CURRENT OF VAPOR THROUGH A MOVING STREAM TO VAPORIZE ANY ORGANICS THE DOW CHEMICAL COMPANY (US) 1980-12-02 US claimed
US-4200698-A BROMO BUTADIENE POLYMER, CHLOROCARBON, EPOXIDIZED CYCLOOLEFIN, POLYAMINE OR POLYAMIDE MICAFIL, AG (CH) 1980-04-29 US claimed