Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | CTSG | P08311 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5335649 | 0.95 | ALOX5 (0.49) | ALOX5PTGS2PPARAHTR2AELANE | |
| SCHEMBL6023397 | 0.93 | ALOX5 (0.47) | ALOX5PTGS2PPARAHTR2AELANE | |
| SCHEMBL8475524 | 0.89 | HMGCR (0.43) | ALOX5PTGS2ELANE | |
| SCHEMBL8347519 | 0.84 | TAAR1 (0.33) | ALOX5PTGS2 | |
| SCHEMBL27660862 | 0.84 | CYP1A2 (0.40) | — | |
| SCHEMBL27980761 | 0.84 | TAAR1 (0.44) | — | |
| SCHEMBL27660863 | 0.84 | CYP1A2 (0.40) | — | |
| SCHEMBL27980507 | 0.83 | TAAR1 (0.43) | — | |
| SCHEMBL456067 | 0.81 | TAAR1 (0.37) | PTGS2 | |
| SCHEMBL11560689 | 0.81 | ALOX5 (0.49) | ALOX5PTGS2PPARAHTR2AELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7541332-B2 | Fungal cell wall synthesis gene | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-02 | — | — | US | disclosed |
| US-20080261272-A1 | FUNGAL CELL WALL SYNTHESIS GENE | EISAI R&D MANAGEMENT CO., LTD (JP) | 2008-10-23 | — | — | US | disclosed |
| US-7375204-B2 | Fungal cell wall synthesis gene | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2008-05-20 | — | — | US | disclosed |
| US-20060234283-A1 | Fungal cell wall synthesis gene | EISAI CO., LTD. (JP) | 2006-10-19 | — | — | US | disclosed |
| US-20060234349-A1 | Fungal cell wall synthesis gene | EISAI CO., LTD. (JP) | 2006-10-19 | — | — | US | disclosed |
| EP-1300464-A1 | FUNGAL CELL WALL SYNTHESIS GENE | Eisai Co., Ltd. (JP) | 2003-04-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060234349-A1 | Fungal cell wall synthesis gene | ERG28, GPI, DPM1 | ALOX5 2868/4885PTGS2 2967/4885PPARA 4804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.