Iohexol

Iohexol

SCHEMBL26501

CC(=O)N(CC(O)CO)c1c(I)c(C(=O)NCC(O)CO)c(I)c(C(=O)NCC(O)CO)c1I

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 1.00
HIF1A Q16665 1/20 1.00
LMNA P02545 4/20 0.95
EGFR P00533 1/20 0.36
SRC P12931 1/20 0.36
MAP2K1 Q02750 7/20 0.33
MAP2K2 P36507 2/20 0.32
PRKCZ Q05513 1/20 0.32
IARS2 Q9NSE4 1/20 0.32
CYP2C9 P11712 1/20 0.32
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
TYMP P19971 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iohexol SCHEMBL37920 1.00 CYP2C19 (1.00) CYP2C19HIF1ALMNAEGFRSRC
Iohexol SCHEMBL8844889 1.00 CYP2C19 (1.00) CYP2C19HIF1ALMNAEGFRSRC
Iohexol SCHEMBL31722694 1.00 CYP2C19 (1.00) CYP2C19HIF1ALMNAEGFRSRC
Iodixanol SCHEMBL22645199 0.99 LMNA (0.97) CYP2C19HIF1ALMNAEGFRSRC
Iohexol SCHEMBL8711982 0.99 CYP2C19 (0.97) CYP2C19HIF1ALMNAEGFRSRC
Iohexol SCHEMBL22719758 0.97 CYP2C19 (0.95) CYP2C19HIF1ALMNAEGFRSRC
Iohexol SCHEMBL3666605 0.97 CYP2C19 (0.95) CYP2C19HIF1ALMNAEGFRSRC
Iodixanol SCHEMBL21546 0.97 LMNA (1.00) CYP2C19HIF1ALMNAEGFRSRC
Iodixanol SCHEMBL8845042 0.97 LMNA (1.00) CYP2C19HIF1ALMNAEGFRSRC
Iodixanol SCHEMBL37712 0.97 LMNA (1.00) CYP2C19HIF1ALMNAEGFRSRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 13835 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144909-A1 TETRAFLUOROETHYLENE COPOLYMER COMPOSITIONS AND ASSOCIATED METHODS W. L. GORE & ASSOCIATES, INC. (US) 2026-05-28 US claimed
CN-120643816-B Drug-coated balloon catheter and preparation method thereof GUANGZHOU WELLLEAD MEDICAL EQUIPMENT Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-122075768-A Degradable embolism microsphere with developing property and preparation method thereof 2026-05-26 CN claimed
US-20260137558-A1 OPHTHALMIC DEVICE Able Tx Ltd. (IL) 2026-05-21 US claimed
CN-122057065-A Ultrasonic-triggered enzymatic crosslinking hydrogel embolic agent and preparation method thereof 中山大学附属第五医院 2026-05-19 CN claimed
CN-122057084-A Valve clamp and preparation method thereof 科凯(南通)生命科学有限公司 2026-05-19 CN claimed
WO-2026101973-A1 IODINATED MULTI-FUNCTIONAL COMPOUNDS WITH ENHANCED HYDROLYTIC STABILITY IN RADIOPAQUE HYDROGELS BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-05-15 WO claimed
WO-2026097940-A1 RADIONUCLIDE-LABELED POLYMER, PREPARATION METHOD THEREFOR, AND USETHEREOF 成都社泰医疗科技有限公司 2026-05-15 WO claimed
CN-122029126-A Method for obtaining iodide ions from a solution comprising an iodine-containing aromatic compound 伯拉考成像股份公司 2026-05-12 CN claimed
US-20260125517-A1 IODINATED MULTI-FUNCTIONAL COMPOUNDS WITH ENHANCED HYDROLYTIC STABILITY IN RADIOPAQUE HYDROGELS BOSTON SCIENTIFIC SCIMED, INC. (US) 2026-05-07 US claimed
EP-0390242-A1 Contrast media NYCOMED IMAGING AS (NO) 1990-10-03 EP claimed
CN-1045528-A CONTRAST MEDIA NYCOMED AS (NO) 1990-09-26 CN claimed
US-4957638-A Method for separating the cellular components of blood samples BECTON DICKINSON AND COMPANY (US) 1990-09-18 US claimed
EP-0190488-B1 SEPARATION OF LYMPHOCYTES AND MONOCYTES FROM BLOOD SAMPLES Becton, Dickinson and Company (US) 1990-07-04 EP claimed
WO-1989011272-A1 HIGH RATIO ACTIVE AGENT:LIPID COMPLEX THE LIPOSOME COMPANY, INC. (US) 1989-11-30 WO claimed
EP-0312713-A2 Improved method for separating the cellular components of blood samples Becton, Dickinson and Company (US) 1989-04-26 EP claimed
US-4816168-A TUBES FOR BLOOD SEPARATION BECTON DICKINSON & COMPANY (US) 1989-03-28 US claimed
EP-0190488-A1 Separation of lymphocytes and monocytes from blood samples Becton, Dickinson and Company (US) 1986-08-13 EP claimed
US-4396597-A Process for the preparation of a sterile injectable physiologically acceptable solution of an X-ray contrast agent and solutions of the X-ray contrast agent and a buffer NYEGAARD & CO. A/S (NO) 1983-08-02 US claimed
US-4278654-A Process for the preparation of a sterile injectable physiologically acceptable solution of an X-ray contrast agent and solutions of the X-ray contrast agent and a buffer NYEGAARD & CO. A/S (NO) 1981-07-14 US claimed