Iohexol

Iohexol

SCHEMBL37920

CC(=O)N(C[C@H](O)CO)c1c(I)c(C(=O)NC[C@H](O)CO)c(I)c(C(=O)NC[C@H](O)CO)c1I

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 1.00
HIF1A Q16665 1/20 1.00
LMNA P02545 4/20 0.95
EGFR P00533 1/20 0.36
SRC P12931 1/20 0.36
MAP2K1 Q02750 7/20 0.33
MAP2K2 P36507 2/20 0.32
PRKCZ Q05513 1/20 0.32
IARS2 Q9NSE4 1/20 0.32
CYP2C9 P11712 1/20 0.32
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
TYMP P19971 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iohexol SCHEMBL8844889 1.00 CYP2C19 (1.00) CYP2C19HIF1ALMNAEGFRSRC
Iohexol SCHEMBL26501 1.00 CYP2C19 (1.00) CYP2C19HIF1ALMNAEGFRSRC
Iohexol SCHEMBL31722694 1.00 CYP2C19 (1.00) CYP2C19HIF1ALMNAEGFRSRC
Iodixanol SCHEMBL22645199 0.99 LMNA (0.97) CYP2C19HIF1ALMNAEGFRSRC
Iohexol SCHEMBL8711982 0.99 CYP2C19 (0.97) CYP2C19HIF1ALMNAEGFRSRC
Iohexol SCHEMBL22719758 0.97 CYP2C19 (0.95) CYP2C19HIF1ALMNAEGFRSRC
Iohexol SCHEMBL3666605 0.97 CYP2C19 (0.95) CYP2C19HIF1ALMNAEGFRSRC
Iodixanol SCHEMBL21546 0.97 LMNA (1.00) CYP2C19HIF1ALMNAEGFRSRC
Iodixanol SCHEMBL8845042 0.97 LMNA (1.00) CYP2C19HIF1ALMNAEGFRSRC
Iodixanol SCHEMBL37712 0.97 LMNA (1.00) CYP2C19HIF1ALMNAEGFRSRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3877 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240282425-A1 AUTHENTICATION METHODS AND SYSTEMS FOR DISPENSED PRESCRIPTIONS LOW GORDON KEITH (US) 2024-08-22 US claimed
US-20200315976-A1 Encapsulation Methods and Compositions PRODO LABORATORIES INC (US) 2020-10-08 US claimed
EP-2915549-B1 A non-degradable, low swelling, water soluble radiopaque hydrogel polymer TRIVASCULAR INC (US) 2019-05-22 EP claimed
EP-3234000-A1 CHITOSAN-BASED HYDROGEL AND APPLICATIONS THEREOF Socovar, L.P. (CA) 2017-10-25 EP claimed
US-20170252304-A1 Encapsulation Methods and Compositions PRODO LABORATORIES INC (US) 2017-09-07 US claimed
WO-2016098057-A1 CHITOSAN-BASED HYDROGEL AND APPLICATIONS THEREOF SOCOVAR, L.P. (CA) 2016-06-23 WO claimed
US-9220880-B2 Methods and devices for delivery of compositions to conduits FEMASYS INC. (US) 2015-12-29 US claimed
EP-2915549-A1 A non-degradable, low swelling, water soluble radiopaque hydrogel polymer TriVascular, Inc. (US) 2015-09-09 EP claimed
CN-104288843-A Spleen and kidney embolic material as well as preparation method and using method thereof SHANGHAI SHIZHENG HEALTHCARE TECHNOLOGIES CO LTD 2015-01-21 CN claimed
US-8840867-B2 Embolizing sclerosing hydrogel Val-Chum Limited Partnership (CA) 2014-09-23 US claimed
EP-1126782-A1 METHOD FOR IMPROVED IMAGING AND PHOTODYNAMIC THERAPY Photogen, Inc. (US) 2001-08-29 EP claimed
WO-2000043045-A1 METHOD FOR IMPROVED RADIATION THERAPY PHOTOGEN, INC. (US) 2000-07-27 WO claimed
WO-2000025665-A1 METHOD FOR IMPROVED IMAGING AND PHOTODYNAMIC THERAPY PHOTOGEN, INC. (US) 2000-05-11 WO claimed
CN-1224622-A Tumor target direction contrast agent ZHANG SHANGQUAN (CN) 1999-08-04 CN claimed
EP-0445182-B1 DELIVERING LASER ENERGY GEN HOSPITAL CORP (US) 1999-01-27 EP claimed
WO-1998046983-A1 RAPID MAGNETIC RESONANCE IMAGING AND MAGNETIC RESONANCE ANGIOGRAPHY OF MULTIPLE ANATOMICAL TERRITORIES WILLIAM BEAUMONT HOSPITAL (US) 1998-10-22 WO claimed
US-5304171-A Catheter devices and methods for delivering GREGORY KENTON W (US) 1994-04-19 US claimed
EP-0445182-A4 DELIVERING LASER ENERGY 1991-11-13 EP claimed
EP-0445182-A1 DELIVERING LASER ENERGY THE GENERAL HOSPITAL CORPORATION (US) 1991-09-11 EP claimed
WO-1990004363-A1 DELIVERING LASER ENERGY THE GENERAL HOSPITAL CORPORATION (US) 1990-05-03 WO claimed