Diphenylmethane

Diphenylmethane

SCHEMBL4409654

NCCC(=O)NN.c1ccc(Cc2ccccc2)cc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.55
CYP1A2 P05177 3/20 0.51
CYP3A4 P08684 3/20 0.51
CYP2D6 P10635 2/20 0.51
CYP2C19 P33261 2/20 0.51
KMT2A Q03164 3/20 0.51
MMP2 P08253 1/20 0.50
PLA2G10 O15496 1/20 0.48
PLA2G2A P14555 1/20 0.48
HDAC8 Q9BY41 3/20 0.47
HDAC6 Q9UBN7 3/20 0.47
MEN1 O00255 2/20 0.47
CALM1 P0DP23 1/20 0.46
LTA4H P09960 1/20 0.44
HDAC2 Q92769 2/20 0.44
LMNA P02545 1/20 0.44
CYP2C9 P11712 2/20 0.44
SLC1A3 P43003 1/20 0.44
SLC1A2 P43004 1/20 0.44
SLC1A1 P43005 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylmethane SCHEMBL4416804 0.85 L3MBTL1 (0.51) L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C19
Biphenyl SCHEMBL4411169 0.84 L3MBTL1 (0.58) L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C19
Benzene SCHEMBL4411983 0.83 KDM4E (0.59) L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C19
Diphenylmethane SCHEMBL3685483 0.81 PLA2G10 (0.57) CYP1A2CYP3A4CYP2D6CYP2C19KMT2A
SCHEMBL967387 0.80 HDAC2 (0.68) L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL1542706 0.78
SCHEMBL6937640 0.77 HDAC1 (0.70) L3MBTL1HDAC8HDAC6HDAC2HDAC3
Carbamic Acid SCHEMBL30312208 0.77 KDM4E (0.56) L3MBTL1CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL8113734 0.76 HDAC1 (0.69) L3MBTL1HDAC8HDAC6HDAC2LMNA
Water SCHEMBL28864249 0.76 HDAC1 (0.68) L3MBTL1HDAC8HDAC6HDAC2HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7638565-B2 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2009-12-29 US disclosed
US-20070054998-A1 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2007-03-08 US disclosed
EP-1686156-A1 POLYACETAL RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2006-08-02 EP disclosed